General notesAfter excision, tissue was fixed in paraformaldehyde and processed to paraffin wax.
Tissue sections were cut to a thickness of 5µm and mounted on positively charged glass slides.
One tissue from each lot was stained by haematoxylin and eosin (H+E) and then microscopically examined to ensure quality.
All tissue is examined / diagnosed by a licensed pathologist and is ethically obtained.
Sex and age of the donor is lot dependent. Please enquire.
Tested applicationsSuitable for:
IHC-P, In situ hybridizationmore details
FunctionActs as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
Tissue specificityExpressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.