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- Secondary antibodies
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Product name
Anti-LAMP1 antibody [1D4B] (FITC)
See all LAMP1 products (22) ...
Description
Rat monoclonal [1D4B] to LAMP1 - Lysosome Marker (FITC)
Conjugation
FITC
Specificity
This antibody is specific to murine CD107a/LAMP1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa).
Tested applications
IHC-Fr, IP, WB, Electron Microscopy, Flow Cytmore details
Cross reactivity
Reacts with
Mouse
Immunogen
Tissue / cell preparation: Plasma membrane fraction of mouse embryo NIH3T3 cell line 1.
Properties
Form
Liquid
Storage instructions
Store at +4°C in the dark.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
1D4B
Isotype
IgG2a
Light chain type
kappa
Research areas
Metabolism >> Pathways and Processes >> Metabolism processes >> Autophagy and mitophagy
Cancer >> Signal transduction >> Autophagy
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Protein Trafficking >> Organelle Proteins
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Lysosome
Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Applications
Show applications key
Our Abpromise guarantee covers the use of ab24871 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
IP
WB
Electron Microscopy
Flow Cyt
Application notes
Electron Microscopy: Use at an assay dependent dilution.
Flow Cyt: Use 1µg for 106 cells.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 45 kDa.
Immunoaffinity chromatography: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Sequence similarities
Belongs to the LAMP family.
Post-translational
modifications
O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.
Cellular localization
Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.
Target information above from: UniProt accessionP11279
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- CD107 antigen like family member A antibody
- CD107 antigen-like family member A antibody
- CD107a antibody
see all
Database links
- Entrez Gene: 16783 Mouse
- SwissProt: P11438 Mouse
- Unigene: 16716 Mouse
- Unigene: 475822 Mouse
References for Anti-LAMP1 antibody [1D4B] (FITC) (ab24871)
This product has been referenced in:
- Buckley JM et al. Increased susceptibility of ST2-deficient mice to polymicrobial sepsis is associated with an impaired bactericidal function. J Immunol 187:4293-9 (2011). Flow Cyt; Mouse.Read more (PubMed: 21911606) »
See 1 publication for this product
Publishing research using ab24871? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"