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Anti-LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

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Overview

Product name

Anti-LAMP1 antibody [LY1C6] - Lysosome Marker
See all LAMP1 products (21) ...

Description

Mouse monoclonal [LY1C6] to LAMP1 - Lysosome Marker

Tested applications

WB, IP, ICC, ICC/IFmore details

Cross reactivity

Reacts with

Mouse, Rat, Hamster

Immunogen

Rat liver lysosomal membrane preparations

Positive control

Highly purified rat lysosomal membrane preparations.

General notes

For maximum product recovery centrifuge the product vial before removing cap.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 50% Glycerol, PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

LY1C6

Isotype

IgG1

Research areas

Cancer >> Signal transduction >> Autophagy
Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Monocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> T Lymphocytic Lineage
Stem Cells >> Hematopoietic Progenitors >> Lymphoid >> B Lymphocytic Lineage
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Protein Trafficking >> Organelle Proteins
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Lysosome
Neuroscience >> Cell Type Marker >> Neuron marker >> Growth Cone
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker

  • Immunocytochemistry/ Immunofluorescence - LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)Immunocytochemistry/ Immunofluorescence - LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab13523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Sequence similarities

Belongs to the LAMP family.

Post-translational
modifications

O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.

Cellular localization

Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane.

Target information above from: UniProt accessionP11279 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • CD107 antigen like family member A antibody
  • CD107 antigen-like family member A antibody
  • CD107a antibody
  • CD107a antigen antibody
  • LAMP 1 antibody
  • LAMP-1 antibody
  • LAMP1 antibody
  • LAMP1_HUMAN antibody
  • LAMPA antibody
  • LGP120 antibody
  • lgpA antibody
  • Lysosomal membrane glycoprotein 120KD antibody
  • Lysosomal Associated Membrane Protein 1 antibody
  • Lysosome associated membrane glycoprotein 1 antibody
  • Lysosome-associated membrane glycoprotein 1 antibody
  • Lysosome-associated membrane protein 1 antibody
  • OTTHUMP00000040663 antibody
see all

Database links

Anti-LAMP1 antibody [LY1C6] - Lysosome Marker images:

  Immunocytochemistry/ Immunofluorescence - LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

Immunocytochemistry/ Immunofluorescence - LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

ab13523 at 1/100 dilution staining LAMP1 in LAMP1 transfected HeLa cells by Immunocytochemistry/ immunofluorescence. A Alexa Fluor® 568 conjugated goat anti mouse was used at 1/50 dilution as secondary.

References for Anti-LAMP1 antibody [LY1C6] - Lysosome Marker (ab13523)

This product has been referenced in:

  • Fort AGet al. In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors. J Biol Chem 286:22875-85 (2011). ICC/IF; Rat.Read more (PubMed: 21536677) »
  • Lanaspa MAet al. Hypertonic stress increases claudin-4 expression and tight junction integrity in association with MUPP1 in IMCD3 cells. Proc Natl Acad Sci U S A 105:15797-802 (2008). ICC/IF; Mouse.Read more (PubMed: 18840681) »

See all 10 publications for this product

Publishing research using ab13523? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"