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Products:Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Overview
Product name
Anti-LANCL2 antibody
See all LANCL2 products (3) ...
Description
Mouse polyclonal to LANCL2
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length LANCL2 protein (Human)
Positive control
LANCL2 transfected 293T cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Whole serum
Purity
Whole antiserum
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Drug resistance >> P glycoproteins
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
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Western blot - LANCL2 antibody (ab67676)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab67676 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).
Target
Relevance
LANCL2 belongs to the LanC like protein family. It is expressed in the brain and testis. LANCL2 is a bystander gene coamplified and overexpressed with epidermal growth factor receptor (EGFR) in 20% of all glioblastomas. Its exogenous expression in a sarcoma cell line decreases the expression of ABCB1 (P glycoprotein 1) and increases cellular sensitivity to an anticancer drug (adriamycin).
Cellular localization
Nucleus. Cytoplasm. Cell membrane.
Alternative names
- G protein coupled receptor 69B antibody
- LanC (bacterial lantibiotic synthetase component C) like 2 antibody
- TASP antibody
- Testis specific adriamycin sensitivity protein antibody
Database links
- Entrez Gene: 55915 Human
- SwissProt: Q9NS86 Human
- Unigene: 595384 Human
Anti-LANCL2 antibody images:
Western blot - LANCL2 antibody (ab67676)
All lanes : Anti-LANCL2 antibody (ab67676) at 1/500 dilution
Lane 1 : LANCL2 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 51 kDa
Observed band size : 51 kDa
References for Anti-LANCL2 antibody (ab67676)
ab67676 has not yet been referenced specifically in any publications.
Publishing research using ab67676? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"