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Western blot - LASS1 antibody (ab56992)
Western blot - LASS1 antibody (ab56992)
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Product Name 

LASS1 antibody

 

See all LASS1 antibodies (3)...

Product type 

Primary antibodies

Description 

Mouse monoclonal to LASS1

Immunogen 

Recombinant fragment: YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF , corresponding to amino acids 301-351 of Human LASS1
BLAST 'YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF ' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Endoplasmic reticulum membrane; Multi-pass membrane protein

Research areas 

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism

Relevance 

LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing mainly one fatty acid donnor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.

 

Alternative names LASS1 antibody (ab56992)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

10715    (Human)

GeneCard

    

GC19M018845    (Human)

Omim

    

606919    (Human)

SwissProt

    

P27544    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2a

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this LASS1 antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

LASS1 antibody images:

Product image  Western blot - LASS1 antibody (ab56992)

Western blot - LASS1 antibody (ab56992)

Western blot against tagged recombinant protein immunogen using ab56992 LASS1 antibody at 1ug/ml. Predicted band size of immunogen is 32 kDa

 
 

Search PubMed (MEDLINE) for references to LASS1

 

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