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Anti-LASS1 antibody (ab56992)

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Overview

Product name

Anti-LASS1 antibody
See all LASS1 products (4) ...

Description

Mouse monoclonal to LASS1

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Recombinant fragment: YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF , corresponding to amino acids 301-351 of Human LASS1

YIVAFAAKVL TGQVHELKDL REYDTAEAQS LKPSKAEKPL RNGLVKDKRF

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2a

Light chain type

kappa

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism

  • Western blot - LASS1 antibody (ab56992)Western blot - LASS1 antibody (ab56992) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab56992 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing mainly one fatty acid donnor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.

Cellular localization

Endoplasmic reticulum membrane; Multi-pass membrane protein

Alternative names

  • CerS1 antibody
  • LAG1 antibody
  • LAG1 homolog ceramide synthase 1 antibody
  • LAG1 longevity assurance homolog 1 antibody
  • LASS 1 antibody
  • Longevity assurance (LAG1 S. cerevisiae) homolog 1 antibody
  • Longevity assurance gene 1 antibody
  • MGC90349 antibody
  • Protein LAG1 antibody
  • UOG 1 protein antibody
  • UOG1 antibody
  • Upstream of GDF1 antibody
see all

Database links

Anti-LASS1 antibody images:

  Western blot - LASS1 antibody (ab56992)

Western blot - LASS1 antibody (ab56992)

Western blot against tagged recombinant protein immunogen using ab56992 LASS1 antibody at 1ug/ml. Predicted band size of immunogen is 32 kDa

References for Anti-LASS1 antibody (ab56992)

ab56992 has not yet been referenced specifically in any publications.

Publishing research using ab56992? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"