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Anti-LASS4 antibody (ab66512)

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Overview

Product name

Anti-LASS4 antibody
See all LASS4 products (3) ...

Description

Rabbit polyclonal to LASS4

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse

Predicted to work with

Rat, Human

Immunogen

A region within synthetic peptide: PIRRKIKPNP VLEKYFLRMK QCPEETQMVL LASQCGLTLR QTQRWFRRRR, corresponding to N terminal amino acids 73-122 of Human LASS4

PIRRKIKPNP VLEKYFLRMK QCPEETQMVL LASQCGLTLR QTQRWFRRRR

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

NIH3T3 cell lysate.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism

  • Western blot - LASS4 antibody (ab66512)Western blot - LASS4 antibody (ab66512) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab66512 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 2.5 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
ELISA titre using peptide based assay: 1/312500.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.

Sequence similarities

Contains 1 homeobox DNA-binding domain.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.

Cellular localization

Nucleus membrane. Endoplasmic reticulum membrane.

Target information above from: UniProt accessionQ9HA82 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • FLJ12089 antibody
  • CerS4 antibody
  • LAG1 homolog ceramide synthase 4 antibody
  • LAG1 longevity assurance homolog 4 antibody
  • LASS 4 antibody
  • LASS4 antibody
  • LASS4 LAG1 homolog ceramide synthase 4 antibody
  • LASS4_HUMAN antibody
  • Trh 1 antibody
  • Trh1 antibody
see all

Database links

Anti-LASS4 antibody images:

  Western blot - LASS4 antibody (ab66512)

Western blot - LASS4 antibody (ab66512)

Anti-LASS4 antibody (ab66512) at 2.5 µg/ml + NIH3T3 cell lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 46 kDa
Observed band size : 46 kDa

References for Anti-LASS4 antibody (ab66512)

ab66512 has not yet been referenced specifically in any publications.

Publishing research using ab66512? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"