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ab48394 has been referenced in 115 publications.

  • Moretton A  et al. Selective mitochondrial DNA degradation following double-strand breaks. PLoS One 12:e0176795 (2017). WB . PubMed: 28453550
  • Vazquez-Cintron EJ  et al. Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery. Sci Rep 7:42923 (2017). PubMed: 28220863
  • Kovatcheva M  et al. ATRX is a regulator of therapy induced senescence in human cells. Nat Commun 8:386 (2017). PubMed: 28855512
  • Li YY  et al. Thioredoxin-2 protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy and apoptosis in H9c2 cardiomyocytes. Am J Transl Res 9:1471-1482 (2017). PubMed: 28386372
  • Gao J  et al. Icariside II, a novel phosphodiesterase 5 inhibitor, protects against H2 O2 -induced PC12 cells death by inhibiting mitochondria-mediated autophagy. J Cell Mol Med 21:375-386 (2017). PubMed: 27642051
  • Liao XH  et al. Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways. Sci Rep 7:43639 (2017). PubMed: 28262728
  • Joachim J  et al. Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy. Curr Biol 27:2123-2136.e7 (2017). PubMed: 28712572
  • Jiang C  et al. GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. PLoS Genet 13:e1006535 (2017). PubMed: 28072828
  • Li J  et al. The Protective Effect of Cordycepin on D-Galactosamine/Lipopolysaccharide-Induced Acute Liver Injury. Mediators Inflamm 2017:3946706 (2017). WB . PubMed: 28522898
  • Jang WH  et al. Interaction of FUN14 domain containing 1, a mitochondrial outer membrane protein, with kinesin light chain 1 via the tetratricopeptide repeat domain. Biomed Rep 6:46-50 (2017). PubMed: 28123706
  • Kim HJ  et al. Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells. Oncotarget 8:6608-6622 (2017). PubMed: 28036259
  • Wang Z  et al. Knockdown of STMN1 enhances osteosarcoma cell chemosensitivity through inhibition of autophagy. Oncol Lett 13:3465-3470 (2017). PubMed: 28529574
  • Mortezavi A  et al. Negative LC3b immunoreactivity in cancer cells is an independent prognostic predictor of prostate cancer specific death. Oncotarget 8:31765-31774 (2017). PubMed: 28423666
  • Luo X  et al. Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration. Redox Biol 13:508-521 (2017). PubMed: 28734243
  • Han D  et al. The Neuroprotective Effects of Muscle-Derived Stem Cells via Brain-Derived Neurotrophic Factor in Spinal Cord Injury Model. Biomed Res Int 2017:1972608 (2017). WB ; Rat . PubMed: 28758111
  • Ma R  et al. Extracellular DNA traps released by acute promyelocytic leukemia cells through autophagy. Cell Death Dis 7:e2283 (2016). PubMed: 27362801
  • Xu Y  et al. Autophagy downregulation contributes to insulin resistance mediated injury in insulin receptor knockout podocytes in vitro. PeerJ 4:e1888 (2016). WB . PubMed: 27077005
  • Wold MS  et al. ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models. Mol Neurodegener 11:76 (2016). PubMed: 27938392
  • Bortnik S  et al. Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. Oncotarget 7:66970-66988 (2016). PubMed: 27556700
  • Xie C  et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy 12:410-23 (2016). IHC . PubMed: 26727396
  • Wang W  et al. Hypoxia-Responsive Mir-301a and Mir-301b Promote Radioresistance of Prostate Cancer Cells via Downregulating NDRG2. Med Sci Monit 22:2126-32 (2016). WB . PubMed: 27327120
  • Perez M  et al. Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1). Oncotarget 7:67033-67046 (2016). WB . PubMed: 27563810
  • Maday S & Holzbaur EL Compartment-Specific Regulation of Autophagy in Primary Neurons. J Neurosci 36:5933-45 (2016). PubMed: 27251616
  • Clough B  et al. K63-Linked Ubiquitination Targets Toxoplasma gondii for Endo-lysosomal Destruction in IFN?-Stimulated Human Cells. PLoS Pathog 12:e1006027 (2016). PubMed: 27875583
  • Li Y  et al. MicroRNA-199a-5p inhibits cisplatin-induced drug resistance via inhibition of autophagy in osteosarcoma cells. Oncol Lett 12:4203-4208 (2016). WB ; Human . PubMed: 27895792
  • Deguise MO  et al. Differential induction of muscle atrophy pathways in two mouse models of spinal muscular atrophy. Sci Rep 6:28846 (2016). WB ; Mouse . PubMed: 27349908
  • Huang C  et al. Thioredoxin interacting protein (TXNIP) regulates tubular autophagy and mitophagy in diabetic nephropathy through the mTOR signaling pathway. Sci Rep 6:29196 (2016). PubMed: 27381856
  • Port SA  et al. The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export. J Biol Chem 291:23068-23083 (2016). PubMed: 27613868
  • Smiles WJ  et al. Protein coingestion with alcohol following strenuous exercise attenuates alcohol-induced intramyocellular apoptosis and inhibition of autophagy. Am J Physiol Endocrinol Metab 311:E836-E849 (2016). PubMed: 27677502
  • Huang Y  et al. Subcellular Evidence for Biogenesis of Autophagosomal Membrane during Spermiogenesis In vivo. Front Physiol 7:470 (2016). WB, IHC ; Turtle . PubMed: 27803675
  • Xue H  et al. A Novel Tumor-promoting Mechanism of IL6 and the Therapeutic Efficacy of Tocilizumab: Hypoxia-induced IL6 Is a Potent Autophagy Initiator in Glioblastoma via the p-STAT3-MIR155-3p-CREBRF Pathway. Autophagy N/A:0 (2016). IHC-P ; Human . PubMed: 27163161
  • Dragich JM  et al. Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. Elife 5:N/A (2016). WB, IHC, ICC/IF . PubMed: 27648578
  • Ow JR  et al. G9a inhibits MEF2C activity to control sarcomere assembly. Sci Rep 6:34163 (2016). IP . PubMed: 27667720
  • Kim KH  et al. The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes. Sci Rep 6:34110 (2016). ICC/IF ; Mouse . PubMed: 27677401
  • Mo J  et al. MicroRNA-195 regulates proliferation, migration, angiogenesis and autophagy of endothelial progenitor cells by targeting GABARAPL1. Biosci Rep 36:N/A (2016). WB ; Human . PubMed: 27623937
  • Liu T  et al. Global analysis of differential gene expression related to long-term sperm storage in oviduct of Chinese Soft-Shelled Turtle Pelodiscus sinensis. Sci Rep 6:33296 (2016). WB, IHC-P . PubMed: 27628424
  • Gai Z  et al. Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice. J Biol Chem 291:2397-411 (2016). PubMed: 26655953
  • Chen Y  et al. FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell. Biochem Biophys Res Commun N/A:N/A (2016). WB ; Human . PubMed: 26993162
  • Zhang A  et al. Natural compound oblongifolin C inhibits autophagic flux, and induces apoptosis and mitochondrial dysfunction in human cholangiocarcinoma QBC939 cells. Mol Med Rep 14:3179-83 (2016). WB ; Human . PubMed: 27499017
  • Park S  et al. Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy. PLoS One 11:e0163029 (2016). Human . PubMed: 27631370
  • Marino M  et al. Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis. Neurobiol Aging 36:492-504 (2015). PubMed: 25085783
  • Matic I  et al. Neuroprotective coordination of cell mitophagy by the F1Fo-ATPase Inhibitory Factor 1 (IF1). Pharmacol Res N/A:N/A (2015). PubMed: 26484591
  • Kyöstilä K  et al. A missense change in the ATG4D gene links aberrant autophagy to a neurodegenerative vacuolar storage disease. PLoS Genet 11:e1005169 (2015). IHC-P ; Dog . PubMed: 25875846
  • Chittaranjan S  et al. Monitoring Autophagic Flux by Using Lysosomal Inhibitors and Western Blotting of Endogenous MAP1LC3B. Cold Spring Harb Protoc 2015:743-50 (2015). PubMed: 26240408
  • Hahn K  et al. TECPR2 Associated Neuroaxonal Dystrophy in Spanish Water Dogs. PLoS One 10:e0141824 (2015). IHC . PubMed: 26555167
  • Zhang J  et al. Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: implications for age-related macular degeneration. Cell Death Dis 6:e1972 (2015). WB, IF . PubMed: 26561782
  • El-Awady AR  et al. Porphyromonas gingivalis evasion of autophagy and intracellular killing by human myeloid dendritic cells involves DC-SIGN-TLR2 crosstalk. PLoS Pathog 10:e1004647 (2015). WB ; Human . PubMed: 25679217
  • Yang M  et al. Autophagy-based survival prognosis in human colorectal carcinoma. Oncotarget 6:7084-103 (2015). IHC . PubMed: 25762626
  • Zhang ZS  et al. Dihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy. Oncol Lett 10:379-383 (2015). WB . PubMed: 26171034
  • Wu S  et al. Expression and clinical significances of Beclin1, LC3 and mTOR in colorectal cancer. Int J Clin Exp Pathol 8:3882-91 (2015). PubMed: 26097572
  • Arensman MD  et al. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Mol Cancer Res 13:1509-19 (2015). PubMed: 26224368
  • Portovedo M  et al. Saturated fatty acids modulate autophagy's proteins in the hypothalamus. PLoS One 10:e0119850 (2015). PubMed: 25786112
  • Ferrier A  et al. Disruption in the autophagic process underlies the sensory neuropathy in dystonia musculorum mice. Autophagy 11:1025-36 (2015). PubMed: 26043942
  • Kandemir FM  et al. Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. Ren Fail 37:518-25 (2015). PubMed: 25613739
  • Xin W  et al. Acetyl-CoA carboxylase 2 suppression rescues human proximal tubular cells from palmitic acid induced lipotoxicity via autophagy. Biochem Biophys Res Commun 463:364-9 (2015). PubMed: 26022126
  • Muñoz-Galván S  et al. MAP17 (PDZKIP1) Expression Determines Sensitivity to the Proteasomal Inhibitor Bortezomib by Preventing Cytoprotective Autophagy and NF?B Activation in Breast Cancer. Mol Cancer Ther 14:1454-65 (2015). PubMed: 25837675
  • Bowie M  et al. Fluoxetine induces cytotoxic endoplasmic reticulum stress and autophagy in triple negative breast cancer. World J Clin Oncol 6:299-311 (2015). WB . PubMed: 26677444
  • Armstrong JL  et al. Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death. J Invest Dermatol 135:1629-1637 (2015). PubMed: 25674907
  • Christian F  et al. PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding. Biochim Biophys Acta 1843:2765-74 (2014). PubMed: 25110345
  • Mahalingam D  et al. Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors. Autophagy 10:1403-14 (2014). PubMed: 24991835
  • Ginet V  et al. A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis. Autophagy 10:603-17 (2014). PubMed: 24487122
  • Ekman M  et al. HIF-mediated metabolic switching in bladder outlet obstruction mitigates the relaxing effect of mitochondrial inhibition. Lab Invest 94:557-68 (2014). PubMed: 24589856
  • Mancuso R  et al. Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice. Neurotherapeutics 11:419-32 (2014). WB ; Mouse . PubMed: 24414863
  • Bae EJ  et al. Phospholipase D1 regulates autophagic flux and clearance of a-synuclein aggregates. Cell Death Differ N/A:N/A (2014). Human . PubMed: 24632948
  • Choi S  et al. Suppression of autophagic activation in the mouse uterus by estrogen and progesterone. J Endocrinol 221:39-50 (2014). Mouse . PubMed: 24443716
  • Chittaranjan S  et al. Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and -resistant triple-negative breast cancer. Clin Cancer Res 20:3159-73 (2014). IHC (PFA fixed) ; Mouse . PubMed: 24721646
  • Buyuklu M  et al. Benefical effects of lycopene against contrast medium-induced oxidative stress, inflammation, autophagy, and apoptosis in rat kidney. Hum Exp Toxicol N/A:N/A (2014). PubMed: 25205736
  • East DA  et al. PMI: a ??m independent pharmacological regulator of mitophagy. Chem Biol 21:1585-96 (2014). WB, ICC/IF . PubMed: 25455860
  • Cabodevilla AG  et al. Cell survival during complete nutrient deprivation depends on lipid droplet-fueled ß-oxidation of fatty acids. J Biol Chem 288:27777-88 (2013). PubMed: 23940052
  • Kalie E  et al. ULK1 Regulates Melanin Levels in MNT-1 Cells Independently of mTORC1. PLoS One 8:e75313 (2013). PubMed: 24066173
  • Ramírez-Peinado S  et al. Glucose-starved cells do not engage in prosurvival autophagy. J Biol Chem 288:30387-98 (2013). WB ; Human . PubMed: 24014036
  • Zhu L  et al. The presence of autophagy in human periapical lesions. J Endod 39:1379-84 (2013). IHC, ICC/IF ; Human . PubMed: 24139258
  • Rajadas J  et al. Enhanced Aß(1-40) production in endothelial cells stimulated with fibrillar Aß(1-42). PLoS One 8:e58194 (2013). WB ; Human . PubMed: 23505467
  • Fang H  et al. Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase. Cell Death Dis 4:e694 (2013). WB . PubMed: 23807223
  • Liikanen I  et al. Oncolytic adenovirus with temozolomide induces autophagy and antitumor immune responses in cancer patients. Mol Ther 21:1212-23 (2013). PubMed: 23546299
  • Liu H  et al. Targeting autophagy as a potential therapeutic approach for melanoma therapy. Semin Cancer Biol 23:352-60 (2013). PubMed: 23831275
  • Howell GM  et al. Augmenting autophagy to treat acute kidney injury during endotoxemia in mice. PLoS One 8:e69520 (2013). WB ; Mouse . PubMed: 23936035
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Sanchez-Alvarez R  et al. Mitochondrial dysfunction in breast cancer cells prevents tumor growth: understanding chemoprevention with metformin. Cell Cycle 12:172-82 (2013). PubMed: 23257779
  • Sanchez-Alvarez R  et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. Cell Cycle 12:289-301 (2013). Human . PubMed: 23257780
  • Avena P  et al. Compartment-specific activation of PPAR? governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle 12:1360-70 (2013). PubMed: 23574724
  • Lizaso A  et al. ß-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation. Autophagy 9:1228-43 (2013). PubMed: 23708524
  • Kalkat M  et al. Placental autophagy regulation by the BOK-MCL1 rheostat. Autophagy 9:2140-53 (2013). PubMed: 24113155
  • Ivanov A  et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol 202:129-43 (2013). WB . PubMed: 23816621
  • Luo Y  et al. EtBr-induced selective degradation of mitochondria occurs via autophagy. Oncol Rep 30:1201-8 (2013). PubMed: 23828262
  • McAlpine F  et al. Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2. Autophagy 9:361-73 (2013). PubMed: 23291478
  • Ucar A  et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun 3:1078 (2012). PubMed: 23011132
  • Martinez-Outschoorn UE  et al. Ketone body utilization drives tumor growth and metastasis. Cell Cycle 11:3964-71 (2012). PubMed: 23082722
  • Zeng R  et al. Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1. Acta Pharmacol Sin 33:91-100 (2012). PubMed: 22158107
  • Zheng X  et al. Acute hypoxia induces apoptosis of pancreatic ß-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis 3:e322 (2012). PubMed: 22695615
  • Periyasamy-Thandavan S  et al. Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim. Breast Cancer Res 14:R52 (2012). WB . PubMed: 22429491
  • Orsi A  et al. Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy. Mol Biol Cell 23:1860-73 (2012). PubMed: 22456507
  • Mah LY  et al. DRAM-1 encodes multiple isoforms that regulate autophagy. Autophagy 8:18-28 (2012). WB . PubMed: 22082963
  • Capparelli C  et al. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle 11:3599-610 (2012). PubMed: 22935696
  • Capparelli C  et al. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production. Cell Cycle 11:2285-302 (2012). PubMed: 22684298
  • Capparelli C  et al. CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth. Cell Cycle 11:2272-84 (2012). PubMed: 22684333
  • Guido C  et al. Metabolic reprogramming of cancer-associated fibroblasts by TGF-ß drives tumor growth: connecting TGF-ß signaling with "Warburg-like" cancer metabolism and L-lactate production. Cell Cycle 11:3019-35 (2012). WB ; Human . PubMed: 22874531
  • Guido C  et al. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth. Oncotarget 3:798-810 (2012). WB ; Human . PubMed: 22878233
  • Carito V  et al. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle 11:3403-14 (2012). Human . PubMed: 22918248
  • Lazova R  et al. Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome. Clin Cancer Res 18:370-9 (2012). IHC-P ; Human . PubMed: 22080440
  • Zeng R  et al. The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion. Ann Hematol 91:407-17 (2012). WB ; Human . PubMed: 21915620
  • Hui L  et al. Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons. Life Sci 91:1159-68 (2012). PubMed: 22580286
  • Hui L  et al. Role of endolysosomes in HIV-1 Tat-induced neurotoxicity. ASN Neuro 4:243-52 (2012). PubMed: 22591512
  • Hou YJ  et al. Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma. Lab Invest 91:1146-57 (2011). PubMed: 21647092
  • Wilkinson S  et al. The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy. Autophagy 7:1295-301 (2011). PubMed: 21808150
  • Grishchuk Y  et al. Beclin 1-independent autophagy contributes to apoptosis in cortical neurons. Autophagy 7:1115-31 (2011). PubMed: 21646862
  • Panyasrivanit M  et al. Induced autophagy reduces virus output in dengue infected monocytic cells. Virology 418:74-84 (2011). PubMed: 21813150
  • Demonbreun AR  et al. Myoferlin is required for insulin-like growth factor response and muscle growth. FASEB J 24:1284-95 (2010). WB ; Mouse . PubMed: 20008164
  • Xu J  et al. Cholesterol trafficking is required for mTOR activation in endothelial cells. Proc Natl Acad Sci U S A 107:4764-9 (2010). PubMed: 20176935
  • Qin L  et al. ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy 6:239-47 (2010). WB ; Mouse . PubMed: 20104019
  • Guikema JE  et al. p53 represses class switch recombination to IgG2a through its antioxidant function. J Immunol 184:6177-87 (2010). WB ; Mouse . PubMed: 20483782
  • Wen HJ  et al. Enhancement of autophagy during lytic replication by the Kaposi's sarcoma-associated herpesvirus replication and transcription activator. J Virol 84:7448-58 (2010). WB ; Human . PubMed: 20484505
  • Martinez-Outschoorn UE  et al. Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NF?B activation in the tumor stromal microenvironment. Cell Cycle 9:3515-33 (2010). PubMed: 20855962
  • Khakpoor A  et al. A role for autophagolysosomes in dengue virus 3 production in HepG2 cells. J Gen Virol 90:1093-103 (2009). PubMed: 19264601
  • Wang AL  et al. Using LC3 to monitor autophagy flux in the retinal pigment epithelium. Autophagy 5:1190-3 (2009). PubMed: 19855195

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