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Anti-LDHA antibody (ab84716)

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Overview

Product name

Anti-LDHA antibody
See all LDHA products (6) ...

Description

Rabbit polyclonal to LDHA

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Sheep, Cow, Chimpanzee

Immunogen

Synthetic peptide designed within residues: ATLKDQLIYN LLKEEQTPQN KITVVGVGAV GMACAISILM KDLADELALV, corresponding to N terminal amino acids 2-51 of Human LDHA (NP_005557)

ATLKDQLIYN LLKEEQTPQN KITVVGVGAV GMACAISILM KDLADELALV

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human placenta lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of carbohydrates
Cancer >> Tumor biomarkers >> Enzymes >> Lactic Dehydrogenase
Signal Transduction >> Metabolism >> Energy Metabolism

  • Western blot - LDHA antibody (ab84716)Western blot - LDHA antibody (ab84716) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab84716 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Involvement in disease

Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:612933]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Post-translational
modifications

ISGylated.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionP00338 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Cell proliferation-inducing gene 19 protein antibody
  • LDH muscle subunit; M LDH antibody
  • PIG19 antibody
  • GSD11 antibody
  • L lactate dehydrogenase A chain antibody
  • L-lactate dehydrogenase A chain antibody
  • l7R2 antibody
  • Lactate dehydrogenase 1, A chain antibody
  • Lactate dehydrogenase A antibody
  • Lactate dehydrogenase A4 antibody
  • Lactate dehydrogenase M antibody
  • LDH A antibody
  • LDH M antibody
  • LDH muscle subunit antibody
  • LDH-A antibody
  • LDH-M antibody
  • LDH1 antibody
  • ldha antibody
  • LDHA_HUMAN antibody
  • LDHM antibody
  • OTTMUSP00000017774 antibody
  • Proliferation-inducing gene 19 antibody
  • Renal carcinoma antigen NY-REN-59 antibody
see all

Database links

see all

Anti-LDHA antibody images:

  Western blot - LDHA antibody (ab84716)

Western blot - LDHA antibody (ab84716)

Anti-LDHA antibody (ab84716) at 1 µg/ml + Human placenta lysate at 10 µg

Secondary
anti-Rabbit IgG HRP at 1/50000 dilution

Predicted band size : 37 kDa
Observed band size : 37 kDa

References for Anti-LDHA antibody (ab84716)

ab84716 has not yet been referenced specifically in any publications.

Publishing research using ab84716? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"