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Product name
Anti-LIMS1 antibody [PINCH-C58]
See all LIMS1 products (6) ...
Description
Mouse monoclonal [PINCH-C58] to LIMS1
Tested applications
WB, IP, ELISAmore details
Cross reactivity
Reacts with
Mouse, Rat, Hamster, Cow, Dog, Human, Monkey
Predicted to work with
Chicken, Xenopus laevis, Zebrafish
Immunogen
Synthetic peptide: CNTKLTLKNKFVEFDMKPV conjugated to KLH, corresponding to amino acids 281/299 of Human LIMS1
CNTKLTLKNKFVEFDMKPV
Positive control
total cell extract from 293T cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 15mM Sodium Azide
Constituents: 0.01M PBS, pH 7.4
Concentration
Concentration information loading...
Purification notes
ab50305 is a purified IgG.
Clonality
Monoclonal
Clone number
PINCH-C58
Myeloma
NS1
Isotype
IgG1
Research areas
Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Signal transducers
Signal Transduction >> Adapters >> Cytoplasmic
Cardiovascular >> Angiogenesis >> Growth Factors >> TGF
Applications
Show applications key
Our Abpromise guarantee covers the use of ab50305 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
IP
ELISA
Application notes
ELISA: Use at an assay dependent dilution.
IP and co-IP: Use at an assay dependent dilution.
WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Effector of integrin and growth factor signaling, coupling surface receptors to downstream signaling molecules involved in the regulation of cell survival, cell proliferation and cell differentiation. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway.
Tissue specificity
Expressed in most tissues except in the brain.
Sequence similarities
Contains 5 LIM zinc-binding domains.
Cellular localization
Cell junction > focal adhesion. Cell membrane.
Target information above from: UniProt accessionP48059
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 2310016J22Rik antibody
- 4921524A02Rik antibody
- AI507642 antibody
see all
Database links
- Entrez Gene: 3987 Human
- Entrez Gene: 110829 Mouse
- Entrez Gene: 499443 Rat
- Entrez Gene: 554019 Zebrafish
- Omim: 602567 Human
- SwissProt: P48059 Human
- SwissProt: Q99JW4 Mouse
- Unigene: 597715 Human
see all
References for Anti-LIMS1 antibody [PINCH-C58] (ab50305)
ab50305 has not yet been referenced specifically in any publications.
Publishing research using ab50305? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"