You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-Laminin alpha 5 antibody [4B12] (ab77175)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-Laminin alpha 5 antibody [4B12]
See all Laminin alpha 5 products (4) ...

Description

Mouse monoclonal [4B12] to Laminin alpha 5

Tested applications

ELISA, Purificationmore details

Cross reactivity

Reacts with

Human

Immunogen

Laminin purified from human placenta.

Positive control

Human embryonic lung (alveolar epithelium). Human kidney.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Ion Exchange Chromatography

Clonality

Monoclonal

Clone number

4B12

Isotype

IgG1

Research areas

Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina

Applications

Show applications key

Our Abpromise guarantee covers the use of ab77175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ELISA

     

  • Purification

     

Application notes

ELISA: Use at an assay dependent dilution. Titer: 1/64000
P: Use at an assay dependent dilution.

Is unsuitable for WB.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Laminins are a family of heterotrimeric extracellular glycoproteins consisting of alpha, beta, and gamma chains. Laminins are thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin alpha 5 (LAMA5) belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Laminin alpha 5 is the alpha chain in the Laminin 15 complex which is a heterotrimer composed of alpha 5/beta 2/gamma 3 which are bound to each other by disulfide bonds into a cross shaped molecule comprising one long and three short arms with globules at each end.

Cellular localization

Secreted; basement membrane.

Alternative names

  • LAMA 5 antibody
  • LAMA5 antibody
  • Laminin alpha 5 chain antibody
  • Laminin subunit alpha 5 antibody
  • Laminin subunit alpha-5 antibody
  • Laminin-10 subunit alpha antibody
  • Laminin-11 subunit alpha antibody
  • Laminin-15 subunit alpha antibody
see all

Database links

References for Anti-Laminin alpha 5 antibody [4B12] (ab77175)

ab77175 has not yet been referenced specifically in any publications.

Publishing research using ab77175? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"