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Product Name
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Laminin alpha 5 antibody
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See all Laminin alpha 5 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to Laminin alpha 5
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Immunogen
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Synthetic peptide derived from the C terminal domain of mouse Laminin alpha 5 protein
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Reacts with
(species key)
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Ms
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Specificity
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ab75344 reacts specifically with Laminin alpha 5 protein.
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Tested applications
(see key)
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IHC-Fr, IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
WB: 1/200 - 1/1000. Predicted molecular weight: 404 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted; basement membrane.
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Research areas
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Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina
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Relevance
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Laminins are a family of heterotrimeric extracellular glycoproteins consisting of alpha, beta, and gamma chains. Laminins are thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin alpha 5 (LAMA5) belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Laminin alpha 5 is the alpha chain in the Laminin 15 complex which is a heterotrimer composed of alpha 5/beta 2/gamma 3 which are bound to each other by disulfide bonds into a cross shaped molecule comprising one long and three short arms with globules at each end.
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Database links
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The links below go to external sites and will open in a new browser window Entrez Gene | | 16776 (Mouse)
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Laminin alpha 5 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Laminin alpha 5
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