Anti-Lipoamide Dehydrogenase antibody (ab20905)

Overview

• Product nameAnti-Lipoamide Dehydrogenase antibodySee all Lipoamide Dehydrogenase primary antibodies ...
• Description
  Rabbit polyclonal to Lipoamide Dehydrogenase
• SpecificityAb20905 recognises Lipoamide Dehydrogenase.
• Tested applicationsELISA more details
• Species reactivity
  Reacts with: Pig
  
• Immunogen

  Full length native protein: Lipoamide Dehydrogenase (Pig Heart)

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.01% Sodium Azide
  Constituents: 20mM Potassium phosphate, 150mM Sodium chloride, pH 7.2
• PurityWhole antiserum
• Purification notesAb20905 is purified by delipidation and defibrination.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Amino acid metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Metabolism
  • Amino Acids

Applications

Target

• FunctionLipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
• Involvement in diseaseNote=Defects in DLD are involved in the development of congenital infantile lactic acidosis.
  Defects in DLD are a cause of maple syrup urine disease (MSUD) [MIM:248600]. MSUD is characterized by mental and physical retardation, feeding problems and a maple syrup odor to the urine. The keto acids of the branched-chain amino acids are present in the urine, resulting from a block in oxidative decarboxylation.
• Sequence similaritiesBelongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
• Post-translational
  modificationsTyrosine phosphorylated.
• Cellular localizationMitochondrion matrix.

Target information above from: UniProt accession P09622 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 397129 Pig
  • SwissProt: P09623 Pig

• Alternative names
  Diaphorase antibodyDihydrolipoamide dehydrogenase antibodyDihydrolipoyl dehydrogenase antibody

  Dihydrolipoyl dehydrogenase mitochondrial antibodydld antibodyDLDH antibodyDLDH_HUMAN antibodyE3 antibodyE3 component of pyruvate dehydrogenase antibodyE3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex antibodyGCSL antibodyGlycine cleavage system L protein antibodyGlycine cleavage system protein L antibodyLAD antibodylipoamide dehydrogenase antibodyLipoamide reductase antibodyLipoyl dehydrogenase antibodymitochondrial antibodyOTTHUMP00000206744 antibodyOTTHUMP00000206746 antibodyOTTHUMP00000206748 antibodyOTTHUMP00000206749 antibodyPHE 3 antibodyPHE3 antibody

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