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Products:Immunology >> Innate Immunity >> Chemokines >> Gamma Chemokines (C)
Overview
Product name
Lymphotactin protein
See all Lymphotactin products (3) ...
Protein description
Highly pure (>98%) recombinant human Lymphotactin.
Expression host
E. coli
Properties
Purification notes
Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg). The biological activity of this product was determined by its ability to chemoattract human T cells using a concentration of 10.0-100.0 ng/ml.
Form
Lyophilised
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration
Concentration information loading...
Additional notes
This product was found to mediate chemotaxis of purified human T cells at concentrations above 20 ng/ml.
Sequence notes
Recombinan t Human Lymphotact in is a 10 kDa protein containing 92 amino acid residues: GSEVSDK RTC VSLTTQRLP V SRIKTYTI TE GSLRAVI FIT KRGLKV CADP QATWV RDVVRSMDRK SNTRN NMIQ TKPTGT QQS TNTAVTL TG
Research areas
Immunology >> Innate Immunity >> Chemokines >> Gamma Chemokines (C)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab9687 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
FuncS: Use at an assay dependent dilution.
SDS-PAGE: Use at an assay dependent dilution.
Protein info
Function
Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
Tissue specificity
Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Sequence similarities
Belongs to the intercrine gamma family.
Cellular localization
Secreted.
Target information above from: UniProt accessionP47992
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for Lymphotactin protein (ab9687)
ab9687 has not yet been referenced specifically in any publications.
Publishing research using ab9687? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"