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Anti-Lysozyme antibody [BGN/06/961] (ab36362)

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Overview

Product name

Anti-Lysozyme antibody [BGN/06/961]
See all Lysozyme products (16) ...

Description

Mouse monoclonal [BGN/06/961] to Lysozyme

Specificity

We have received mixed feedback on the reactivity of this antibody with the chicken protein and are therefore not able to conclude whether this antibody works or not on chicken.

Tested applications

IHC-P, WB, ELISAmore details

Cross reactivity

Reacts with

Mouse, Human

Immunogen

Full length native Lysozyme / Muramidase protein (purified) (Human urine)

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Monoclonal

Clone number

BGN/06/961

Isotype

IgG2a

Research areas

Tags & Cell Markers >> Subcellular Markers >> Organelles >> Lysosome
Cardiovascular >> Blood >> Other
Immunology >> Adaptive Immunity >> T Cells >> Cytotoxic Cells
Immunology >> Innate Immunity >> Macrophage / Inflamm.

Applications

Show applications key

Our Abpromise guarantee covers the use of ab36362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

Involvement in disease

Defects in LYZ are a cause of amyloidosis type 8 (AMYL8) [MIM:105200]; also known as systemic non-neuropathic amyloidosis or Ostertag-type amyloidosis. AMYL8 is a hereditary generalized amyloidosis due to deposition of apolipoprotein A1, fibrinogen and lysozyme amyloids. Viscera are particularly affected. There is no involvement of the nervous system. Clinical features include renal amyloidosis resulting in nephrotic syndrome, arterial hypertension, hepatosplenomegaly, cholestasis, petechial skin rash.

Sequence similarities

Belongs to the glycosyl hydrolase 22 family.

Cellular localization

Secreted.

Target information above from: UniProt accessionP61626 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • 1 4 beta n acetylmuramidase c antibody
  • 1 antibody
  • 14 beta N acetylmuramidase antibody
  • 14 beta N acetylmuramidase C antibody
  • 4-beta-N-acetylmuramidase C antibody
  • EC 3.2.1.17 antibody
  • LYSC_HUMAN antibody
  • Lysosyme antibody
  • Lysozyme (renal amyloidosis) antibody
  • Lysozyme C antibody
  • Lysozyme C precursor antibody
  • Lyz antibody
  • LZM antibody
  • Muramidase antibody
  • Renal amyloidosis antibody
see all

Database links

References for Anti-Lysozyme antibody [BGN/06/961] (ab36362)

This product has been referenced in:

  • Ballon Get al. Kaposi sarcoma herpesvirus (KSHV) vFLIP oncoprotein induces B cell transdifferentiation and tumorigenesis in mice. J Clin Invest 121:1141-53 (2011). IHC-P; Mouse.Read more (PubMed: 21339646) »
  • Shorning BYet al. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut : (2011). Mouse.Read more (PubMed: 21813469) »

See all 5 publications for this product

Publishing research using ab36362? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"