Overview

  • Product name
    M344
  • Description
    HDAC inhibitor. Shows selectivity for HDAC6.
  • Biological description
    HDAC inhibitor (IC50 = 100 nM). Shows selectivity for HDAC6. Inhibits growth of various cancer cells. Apoptosis inducer.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Yeung A  et al. HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation. Biomed Pharmacother 66:232-6 (2012). Read more (PubMed: 22436652) »
  • Li X & Chen BD Histone Deacetylase Inhibitor M344 Inhibits Cell Proliferation and Induces Apoptosis in Human THP-1 Leukemia Cells. Am J Biomed Sci 1:352-363 (2009). Read more (PubMed: 20526416) »
  • Riessland M  et al. The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells. Hum Genet 120:101-10 (2006). Read more (PubMed: 16724231) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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