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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MADD antibody (ab85150)
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Product Name
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MADD antibody
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See all MADD antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to MADD
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Immunogen
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A synthetic peptide from the internal sequence of human MADD (NM_000126).
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Reacts with
(species key)
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Hu, Ms, Rat
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/50 - 1/200.
Peptide ELISA: 1/1000 - 1/10000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human fetal stomach tissue.
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Cellular localization
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Mitochondrion matrix
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Signal Transduction >> Metabolism >> Mitochondrial
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Relevance
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ETFA (MADD) participates in catalyzing the initial step of the mitochondrial fatty acid beta oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric,2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 2% BSA Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified by peptide affinity column.
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MADD antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for MADD antibody images, references, products related to ab85150 and other tools.
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MADD antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MADD antibody (ab85150)
ab85150, at a 1/100 dilution, staining MADD in human fetal stomach tissue.
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Search PubMed (MEDLINE) for references to MADD
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MADD antibody - more information
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Customer reviews (feedback) regarding MADD antibody |
Customer FAQs regarding MADD antibody |
Protocols for MADD antibody |
Price and availability of products related to MADD antibody |
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MADD antibody - related products:
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MADD antibody - other tools:
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Contact Abcam with a Technical Enquiry about MADD antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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