![Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - MAGE 1 antibody [SPM282] (ab25834) image](#ab25834_1.JPG)
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Products:Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Overview
Product name
Anti-MAGE 1 antibody [SPM282]
See all MAGE 1 products (9) ...
Description
Mouse monoclonal [SPM282] to MAGE 1
Specificity
ab25834 recognises MAGE-1.
Tested applications
IF, IHC-P, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Rat, Dog
Immunogen
Partially purified, full length recombinant human MAGE-1 protein
Positive control
Colo32 cells Germ cells in testis.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: BSA, 10mM PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
SPM282
Isotype
IgG1
Light chain type
kappa
Research areas
Cancer >> Tumor biomarkers >> Tumor antigens
Cancer >> Tumor immunology >> Tumor-associated antigens
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
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Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - MAGE 1 antibody [SPM282] (ab25834)
![Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - MAGE 1 antibody [SPM282] (ab25834) image](/ps/datasheet/Images/25/ab25834/ab25834_1.JPG)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab25834 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IF: Use at an assay dependent dilution.
IHC-P: 1/25Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB: Use a concentration of 0.5 - 1.0 µg/ml.Predicted molecular weight: 44 kDa.
Target
Relevance
The MAGE 1 gene is a member of the melanoma antigen encoding gene family. These genes encode for HLA-restricted tumor associated rejection antigens recognized by cytotoxic T lymphocytes. Some of these target antigens may be potentially useful for cancer specific immunotherapy. The expression of MAGE genes has been reported not only in melanoma but also in various other malignant tumors such as hepatocellular carcinoma and germ cell tumors.
Cellular localization
Cytoplasmic
Alternative names
- Antigen MZ2 E antibody
- MAGE 1 antigen antibody
- MAGE1 antibody
see all
Database links
- Entrez Gene: 4100 Human
- Entrez Gene: 493750 Rat
- Omim: 300016 Human
- SwissProt: P43355 Human
Anti-MAGE 1 antibody [SPM282] images:
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - MAGE 1 antibody [SPM282] (ab25834)
ab25834 staining MAGE 1 in Human testis by Immunohistochemisty of formalin-fixed, parrafin embedded tissue.
References for Anti-MAGE 1 antibody [SPM282] (ab25834)
ab25834 has not yet been referenced specifically in any publications.
Publishing research using ab25834? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"