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Products:Cancer >> Tumor immunology >> Tumor-associated antigens
Overview
Product name
Anti-MAGEA4 antibody
See all MAGEA4 products (3) ...
Description
Mouse monoclonal to MAGEA4
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: TSPDAESLFR EALSNKVDEL AHFLLRKYRA KELVTKAEML ERVIKNYKRC FPVIFGKASE SLKMIFGIDV KEVD, corresponding to amino acids 98-172 of Human MAGEA4
TSPDAESLFR EALSNKVDEL AHFLLRKYRA KELVTKAEML ERVIKNYKRC FPVIFGKASE SLKMIFGIDV KEVD
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2b
Light chain type
kappa
Research areas
Cancer >> Tumor biomarkers >> Tumor antigens
Cancer >> Tumor immunology >> Tumor-associated antigens
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Western blot - MAGEA4 antibody (ab55512)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55512 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Tissue specificity
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
Sequence similarities
Contains 1 MAGE domain.
Target information above from: UniProt accessionP43358
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Cancer/testis antigen 1.4 antibody
- CT1.4 antibody
- MAGA4_HUMAN antibody
see all
Database links
- Entrez Gene: 4103 Human
- Omim: 300175 Human
- SwissProt: P43358 Human
- Unigene: 37107 Human
Anti-MAGEA4 antibody images:
Western blot - MAGEA4 antibody (ab55512)
MAGEA4 antibody (ab55512) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-MAGEA4 antibody (ab55512)
This product has been referenced in:
- Cruz CRet al. Improving T-cell Therapy for Relapsed EBV-Negative Hodgkin Lymphoma by Targeting Upregulated MAGE-A4. Clin Cancer Res 17:7058-66 (2011). IHC; Human.Read more (PubMed: 21908573) »
- Shafer JAet al. Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin lymphoma. Leuk Lymphoma 51:870-80 (2010).Read more (PubMed: 20367572) »
See all 2 publications for this product
Publishing research using ab55512? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"