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Products:Cancer >> Tumor immunology >> Tumor-associated antigens
Overview
Product name
Anti-MAGEL2 antibody
See all MAGEL2 products (2) ...
Description
Rabbit polyclonal to MAGEL2
Tested applications
ELISA, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
KLH conjugated synthetic peptide (10-30 amino acids in length) at the C terminus of last 50 amino acids of human MAGEL1.
Positive control
IHC-P: Human hepatocarcinoma tissue
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Tumor biomarkers >> Tumor antigens
Cancer >> Tumor immunology >> Tumor-associated antigens
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MAGEL1 antibody (ab60052)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab60052 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000ELISA: 1/1000
IHC-P: 1/50 - 1/100.
Target
Relevance
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Alternative names
- Mage-l2 antibody
- MAGE-like 2 antibody
- MAGE-like protein 2 antibody
see all
Database links
- Entrez Gene: 54551 Human
- Omim: 605283 Human
- SwissProt: Q9UJ55 Human
- Unigene: 141496 Human
Anti-MAGEL2 antibody images:
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MAGEL1 antibody (ab60052)
ab60052, at a 1/50 dilution, staining MAGEL1 in formalin fixed and paraffin embedded hepatocarcinoma tissue sections by Immunohistochemistry. The primary antibody was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
References for Anti-MAGEL2 antibody (ab60052)
ab60052 has not yet been referenced specifically in any publications.
Publishing research using ab60052? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"