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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MAGEL1 antibody (ab60052)
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Product Name
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MAGEL2 antibody
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to MAGEL2
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Immunogen
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KLH conjugated synthetic peptide (10-30 amino acids in length) at the C terminus of last 50 amino acids of human MAGEL1.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ELISA, IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/1000.
IHC-P: 1/50 - 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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IHC-P: Human hepatocarcinoma tissue
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Research areas
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Cancer >> Tumor biomarkers >> Tumor antigens
Cancer >> Tumor immunology >> Tumor-associated antigens
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Relevance
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Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGE is unknown, may play a role in embryonal development and tumor transformation or aspects of tumor progression.
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MAGEL2 antibody (ab60052) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.250 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MAGEL2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for MAGEL2 antibody images, references, products related to ab60052 and other tools.
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MAGEL2 antibody images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MAGEL1 antibody (ab60052)
ab60052, at a 1/50 dilution, staining MAGEL1 in formalin fixed and paraffin embedded hepatocarcinoma tissue sections by Immunohistochemistry. The primary antibody was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
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Search PubMed (MEDLINE) for references to MAGEL2
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MAGEL2 antibody - more information
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Customer reviews (feedback) regarding MAGEL2 antibody |
Customer FAQs regarding MAGEL2 antibody |
Protocols for MAGEL2 antibody |
Price and availability of products related to MAGEL2 antibody |
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MAGEL2 antibody - related products:
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MAGEL2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about MAGEL2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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