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Products:Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules
Overview
Product name
Anti-MAP 2a + 2b + 2c antibody
See all MAP 2a + 2b + 2c products (3) ...
Description
Sheep polyclonal to MAP 2a + 2b + 2c
Tested applications
WB, IHC-Fr, IHC-Pmore details
Cross reactivity
Reacts with
Mouse, Rat
Immunogen
A synthetic peptide as a part of rat and mouse MAP 2a + 2b + 2c conjugated to an immunogenic carrier protein.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> MT Associated Proteins >> MAP
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules
Applications
Show applications key
Our Abpromise guarantee covers the use of ab72354 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
IHC-Fr
IHC-P
Application notes
IHC-P: Use at a concentration of 10 - 50 µg/ml. Antigen retrieval is recommended.
IHC-Fr: Use at a concentration of 10 - 50 µg/ml.
WB: Use at a concentration of 10 - 50 µg/ml. Predicted molecular weight: 202 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 belongs to the microtubule associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isforms have been described.
Cellular localization
Cytoplasm, cytoskeleton (Probable).
Alternative names
- MAP 2 antibody
- MAP2A antibody
- MAP2B antibody
see all
Database links
- Entrez Gene: 17756 Mouse
- Entrez Gene: 25595 Rat
- SwissProt: P20357 Mouse
- SwissProt: P15146 Rat
- Unigene: 10484 Rat
References for Anti-MAP 2a + 2b + 2c antibody (ab72354)
ab72354 has not yet been referenced specifically in any publications.
Publishing research using ab72354? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"