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Overview

  • Product nameMAP1LC3B2 protein
  • Protein descriptionRecombinant full length mature Human MAP1LC3B2 (amino acids 1-120) with an N terminal His tag; 140 amino acids with tag, Predicted MWt 16.2 kDa (UniProt A6NCE7).
  • Uniprot accessionA6NCE7
  • Molecular weight16.200kDa inclusive of tags
  • Protein length120 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab106858 is purified using conventional chromatography techniques.
  • Mass spectrometryMALDI-TOF
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
  • Concentration information loading...
  • SequenceMGSSHHHHHHSSGLVPRGSHMPSEKTFKQRRTFEQRVEDV RLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYE SEKDEDGFLYMVCASQETFG
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab106858 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    MS MS: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        ATG8GMAP1LC3B2Microtubule associated protein 1 light chain 3 beta 2
        Microtubule associated proteins 1A/1B light chain 3B like proteinMicrotubule-associated proteins 1A/1B light chain 3 beta 2Microtubule-associated proteins 1A/1B light chain 3B-likeMP3B2_HUMAN
      see all
  • FunctionProbably involved in formation of autophagosomal vacuoles (autophagosomes).
  • Sequence similaritiesBelongs to the MAP1 LC3 family.
  • Post-translational
    modifications    The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I (By similarity). This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II.
  • Cellular localizationCytoplasm > cytoskeleton. Endomembrane system. Cytoplasmic vesicle > autophagosome membrane. LC3-II binds to the autophagic membranes.

    • Target information above from: UniProt accession A6NCE7 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    MAP1LC3B2 protein images

    • SDS-PAGE - MAP1LC3B2 protein (ab106858)
      SDS-PAGE - MAP1LC3B2 protein (ab106858)
      15% SDS-PAGE analysis of 3µg ab106858.

    References for MAP1LC3B2 protein (ab106858)

    ab106858 has not yet been referenced specifically in any publications.

    Publishing research using ab106858 ? Please let us know so that we can cite the reference in this datasheet

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