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Product Name 

MAP1a + MAP1b antibody [MP-1]

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [MP-1] to MAP1a + MAP1b

Immunogen 

Rat brain microtubule-associated proteins (MAPs)

Reacts with 
(species key)

Rat

Specificity 

No cross reactivity with other proteins.

Tested applications 
(see key)

IHC-Fr, IHC-P, WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
IHC-P: Use at a concentration of 1 - 2 µg/ml.
IHC-Fr: Use at a concentration of 1 - 2 µg/ml. Use formalin or acetone fixed tissues.
WB: Use at a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: MAP1a 306 kDa; MAP1b 271 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Neuroscience >> Cell Type Marker >> Neuron marker >> Axon marker
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> MT Associated Proteins >> MAP
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules

Relevance 

Microtubules are the ubiquitous cytoskeletal structural components that are involved in intracellular transport. They are composed of tubulin and microtubule-associated proteins (MAPs). MAP1 is one of the major neuronal MAPs as well as being the largest (350KD). MAPs include MAP1A, MAP1B , and MAP2. MAP1a is a single-copy gene spanning 10.5 kb. MAP1a coding sequence is contained in five exons. MAP1B is encoded as a polyprotein that is processed to form a complex N-terminal microtubule-binding domain.

 

Alternative names MAP1a + MAP1b antibody [MP-1] (ab82283)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

29456    (Rat)
25152    (Rat)

SwissProt

    

P34926    (Rat)
P15205    (Rat)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

MP-1

Isotype 

IgG1

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 1.2% Sodium acetate, 2mg/ml BSA

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

ab82283 is purified using goat anti-mouse IgG affinity chromatography.

Form 

Liquid

Concentration 

0.100 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MAP1a + MAP1b antibody [MP-1] is on this datasheet. But please do contact us if you would like any reassurance!


 

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