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Anti-MAP2 antibody (ab24640)

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Overview

Product name

Anti-MAP2 antibody
See all MAP2 products (18) ...

Description

Rabbit polyclonal to MAP2

Tested applications

IHC-P, Electron Microscopy, ICC/IF, WB, IFmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Predicted to work with

all Mammals

Immunogen

Brain MAP2 (Cow)

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

antiserum

Purity

Whole antiserum

Purification notes

ab24640 was electrophoretically purified from heat stable MAP fraction.

Clonality

Polyclonal

Isotype

IgG

Applications

Show applications key

Our Abpromise guarantee covers the use of ab24640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

EM: Use at an assay dependent dilution (PMID 19020041).
ICC/IF: 1/200 (PMID 18403755).
IF: 1/1000.
IHC-P: 1/200 (PMID 18403755).
IHC-FrFl: Use at an assay dependent dilution (PMID 20154682).
WB: 1/1000.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.

Sequence similarities

Contains 3 Tau/MAP repeats.

Post-translational
modifications

MAP2A/c is phosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.

Cellular localization

Cytoplasm > cytoskeleton.

Target information above from: UniProt accessionP11137 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DKFZp686I2148 antibody
  • Dendrite specific MAP antibody
  • Dendrite specific MAP antibody
  • DKFZp686I2148 antibody
  • MAP 2 antibody
  • MAP-2 antibody
  • MAP2 antibody
  • MAP2_HUMAN antibody
  • MAP2A antibody
  • MAP2B antibody
  • MAP2C antibody
  • Microtubule associated protein 2 antibody
  • Microtubule-associated protein 2 antibody
  • Mtap 2 antibody
  • Mtap 2 antibody
see all

References for Anti-MAP2 antibody (ab24640)

This product has been referenced in:

  • Anderson Det al. Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes. Nat Neurosci 13:333-7 (2010). IHC-FrFl; Rat.Read more (PubMed: 20154682) »
  • Grubb MS & Burrone J Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature 465:1070-4 (2010). ICC/IF; Rat.Read more (PubMed: 20543823) »

See all 7 publications for this product

Publishing research using ab24640? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"