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Product Name 

MAP2a + MAP2b antibody [1.B.642] (Biotin)

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [1.B.642] to MAP2a + MAP2b (Biotin)

Immunogen 

300kDa MAP2 protein from bovine brain

Reacts with 
(species key)

Hu, Ms, Rat, Chk, Cow

Specificity 

ab63518 reacts with high molecular weight isoforms of MAP2 (MAP2a and MAP2b), but not with the low molecular weight isoform MAP2c.

Tested applications 
(see key)

IHC-Fr, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-Fr: 1/500.
WB: Use at an assay dependent dilution.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Dendrites or cell bodies of neurons.

Cellular localization 

Cytoplasm, cytoskeleton

Research areas 

Neuroscience >> Cell Type Marker >> Neuron marker >> Dendrite marker
Tags & Cell Markers >> Cell Type Markers >> Neuroscience Markers >> Neuronal
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> MT Associated Proteins >> MAP
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules

Relevance 

MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene.

 

MAP2a + MAP2b antibody [1.B.642] (Biotin) (ab63518)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

424001    (Chicken)
281294    (Cow)
4133    (Human)
17756    (Mouse)
25595    (Rat)

Omim

    

157130    (Human)

SwissProt

    

P11137    (Human)
P20357    (Mouse)
P15146    (Rat)

Unigene

    

368281    (Human)
10484    (Rat)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

1.B.642

Isotype 

IgG1

Purity 

Protein G purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 0.01M PBS, pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Conjugation 

Biotin

Concentration 

0.050 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MAP2a + MAP2b antibody [1.B.642] (Biotin) is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to MAP2a + MAP2b

 

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