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Anti-MAP2a + MAP2b antibody [AP20] (FITC) (ab24279)

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Overview

Product name

Anti-MAP2a + MAP2b antibody [AP20] (FITC)
See all MAP2a + MAP2b products (3) ...

Description

Mouse monoclonal [AP20] to MAP2a + MAP2b (FITC)

Conjugation

FITC

Specificity

ab24279 reacts with the high molecular weight forms (2a & 2b) of MAP-2 but not with the low molecular weight form (2c). It reacts with dendrites and cell bodies of neurons.

Tested applications

IHC-Fr, WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Chicken, Human

Immunogen

The details of the immunogen for this antibody are not available.

Properties

Form

Liquid

Storage instructions

Store at +4°C in the dark. Do not freeze.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: 1.0% BSA, 0.01M PBS, 2.0mM EDTA. pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

AP20

Isotype

IgG1

Research areas

Neuroscience >> Cell Type Marker >> Neuron marker >> Dendrite marker
Tags & Cell Markers >> Cell Type Markers >> Neuroscience Markers >> Neuronal
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microtubules >> MT Associated Proteins >> MAP
Neuroscience >> Cell Type Marker >> Neuron marker >> Soma marker
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Microtubules

Applications

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Our Abpromise guarantee covers the use of ab24279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IHC-Fr

     

  • WB

     

Application notes

IHC-Fr: 1/500. WB: Use at an assay dependent dilution. Detects a band of approximately 300 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene.

Cellular localization

Cytoplasm, cytoskeleton

Alternative names

  • Microtubule associated protein 2 antibody
  • DKFZp686I2148 antibody
  • MAP 2 antibody
  • MAP 2a antibody
  • MAP 2b antibody
  • MAP dendrite specific antibody
  • MAP2 antibody
  • MAP2A antibody
  • MAP2B antibody
  • Microtubule associated protein 2 antibody
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Database links

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References for Anti-MAP2a + MAP2b antibody [AP20] (FITC) (ab24279)

This product has been referenced in:

  • Schober <i></i> et al. Microfluidics and biosensors as tools for NanoBioSystems research with applications in the "Life Science" Materials Science and Engineering: B 169:174-181 (2009). ICC/IF; Mouse.Read more (PubMed: ) »
  • Guzman Ret al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI. Proc Natl Acad Sci U S A 104:10211-6 (2007).Read more (PubMed: 17553967) »

See all 3 publications for this product

Publishing research using ab24279? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"