![Immunohistochemistry (Paraffin-embedded sections) - MAP4K1 antibody [EP630Y] (ab33910) image](#33910a.jpg)
![Western blot - MAP4K1 antibody [EP630Y] (ab33910) image](#33910.jpg)
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Product name
Anti-MAP4K1 antibody [EP630Y]
See all MAP4K1 products (7) ...
Description
Rabbit monoclonal [EP630Y] to MAP4K1
Specificity
ab33910 recognises hematopoietic progenitor kinase 1 (HPK1).
Tested applications
WB, Flow Cyt, IHC-Pmore details
Cross reactivity
Reacts with
Human
Does not react with
Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in the N term of human HPK1 (Human)
Positive control
Raji cell lysate
General notes
Produced under U.S. Patent No. 5,675,063.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
EP630Y
Isotype
IgG
Research areas
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Small G Proteins >> Regulators
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> MAPK Pathway
Applications
Show applications key
Our Abpromise guarantee covers the use of ab33910 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/5000 - 1/20000. Predicted molecular weight: 97 kDa.
Flow Cyt
Flow Cyt: 1/60.Flow Cyt: 1/60.
IHC-P: Use at an assay dependent dilution.
Application notes
Is unsuitable for ,ICC or IP.
Target
Function
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.
Tissue specificity
Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.
Sequence similarities
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 CNH domain.
Contains 1 protein kinase domain.
Target information above from: UniProt accessionQ92918
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Hematopoietic progenitor kinase 1 antibody
- Hematopoietic progenitor kinase antibody
- HPK1 antibody
see all
Database links
- Entrez Gene: 11184 Human
- Omim: 601983 Human
- SwissProt: Q92918 Human
- Unigene: 95424 Human
Anti-MAP4K1 antibody [EP630Y] images:
Immunohistochemistry (Paraffin-embedded sections) - MAP4K1 antibody [EP630Y] (ab33910)
![Immunohistochemistry (Paraffin-embedded sections) - MAP4K1 antibody [EP630Y] (ab33910)](/ps/datasheet/Images/33/ab33910/33910a.jpg)
Immunohistochemical analysis of paraffin-embedded human lymph node using anti-HPK1
Western blot - MAP4K1 antibody [EP630Y] (ab33910)
![Western blot - MAP4K1 antibody [EP630Y] (ab33910)](/ps/datasheet/Images/33/ab33910/33910.jpg)
Anti-MAP4K1 antibody [EP630Y] (ab33910) at 1/5000 dilution + Raji cell lysate
Predicted band size : 97 kDa
Observed band size : 97 kDa
References for Anti-MAP4K1 antibody [EP630Y] (ab33910)
This product has been referenced in:
- Palmer RD et al. Pediatric malignant germ cell tumors show characteristic transcriptome profiles. Cancer Res 68:4239-47 (2008). IHC-P; Human.Read more (PubMed: 18519683) »
See 1 publication for this product
Publishing research using ab33910? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"