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Read our guarantee »Anti-MAPKAP Kinase 2 antibody [E341]
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Rabbit monoclonal [E341] to MAPKAP Kinase 2
ab32567 recognises MAPKAP Kinase-2.
WB, IPmore details
Reacts with
Mouse, Rat, Human
A synthetic peptide corresponding to residues near C-terminus of human MAPKKAP Kinase-2.
Hela cell lysate.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Concentration information loading...
IgG fraction
Monoclonal
E341
IgG
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> MAPK Pathway
Signal Transduction >> Cytoskeleton / ECM >> Cytoskeleton >> Microfilaments >> Actin etc >> Actin
Cardiovascular >> Blood >> Other
Western blot - MAPKAP Kinase 2 antibody [E341] (ab32567)
(enlarge)
Our Abpromise guarantee covers the use of ab32567 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: 1/200.
WB: 1/500 - 1/1000. Detects a band of approximately 46 kDa (predicted molecular weight: 46 kDa).
Is unsuitable for FACS, ICC or IHC.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.
Expressed in all tissues examined.
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
Phosphorylated and activated by MAP kinase.
Target information above from: UniProt accessionP49137
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Western blot - MAPKAP Kinase 2 antibody [E341] (ab32567)
![Western blot - MAPKAP Kinase 2 antibody [E341] (ab32567)](/ps/datasheet/Images/32/ab32567/ab32567wb.gif)
Anti-MAPKAP Kinase 2 antibody [E341] (ab32567) at 1/1000 dilution + Hela cell lysate
Predicted band size : 46 kDa
Observed band size : 46 kDa
ab32567 has not yet been referenced specifically in any publications.
Publishing research using ab32567? Please let us know so that we can cite the reference in this datasheet
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