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Product Name
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MARCO antibody [PAL-1]
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [PAL-1] to MARCO
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Immunogen
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Hamster alveolar macrophages
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Reacts with
(species key)
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Hm
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Specificity
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This antibody is specific for MARCO.
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Tested applications
(see key)
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Flow Cyt, IHC-Fr, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use at an assay dependent dilution.
Use 10µl of the suggested working dilution to label 106 cells in 100µl.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Membrane; single pass type II membrane protein.
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Research areas
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Immunology >> Immune System Diseases >> Antiviral Signaling
Microbiology >> Protein >> Human Protein >> Defensin
Immunology >> Innate Immunity >> Macrophage / Inflamm.
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Relevance
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MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram negative and Gram positive bacteria via an extracellular, C terminal, scavenger receptor cysteine rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. MARCO may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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PAL-1
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Myeloma
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P3U1
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Isotype
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IgM
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Purity
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Purified IgM
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Storage buffer
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Preservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified IgM prepared by ammonium sulphate precipitation from tissue culture supernatant.
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C. Do not freeze.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MARCO antibody [PAL-1] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to MARCO
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MARCO antibody [PAL-1] - more information
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Customer reviews (feedback) regarding MARCO antibody [PAL-1] |
Customer FAQs regarding MARCO antibody [PAL-1] |
Protocols for MARCO antibody [PAL-1] |
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MARCO antibody [PAL-1] - other tools:
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