Overview

  • Product nameAnti-MCC antibody
    See all MCC primary antibodies
  • Description
    Mouse monoclonal to MCC
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: DIVELNKRLQ QTERERDLLE KKLAKAQCEQ SHLMREHEDV QERTTLRYEE RITELHSVIA ELNKKIDRLQ GTTIREEDEY SELRSELSQS QHEVNEDSRS , corresponding to amino acids 31-130 of Human MCC

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • Clonality Monoclonal
  • IsotypeIgG1
  • Light chain typekappa
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab55489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCandidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.
    • Tissue specificityExpressed in a variety of tissues.
    • Sequence similaritiesBelongs to the MCC family.
    • Cellular localizationCell membrane. Nucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • Colorectal mutant cancer protein antibody
      • CRCM_HUMAN antibody
      • DKFZp762O1615 antibody
      • FLJ38893 antibody
      • FLJ46755 antibody
      • MCC 1 antibody
      • MCC antibody
      • MCC1 antibody
      • Mutated in colorectal cancers antibody
      • Protein MCC antibody
      see all

    Anti-MCC antibody images

    • Western blot against tagged recombinant protein immunogen using ab55489 MCC antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-MCC antibody (ab55489)

    ab55489 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab55489.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"