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Product Name 

MCP1 antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to MCP1

Immunogen 

Recombinant full length protein (Human).

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: Use at a concentration of 0.5 µg/ml.
WB: Use at a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Secreted

Research areas 

Cancer >> Cancer Metabolism >> Response to hypoxia
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Leukocyte recruitment >> Chemokines
Immunology >> Innate Immunity >> Cytokines >> Other
Immunology >> Innate Immunity >> Chemokines >> Beta Chemokines (CC)
Immunology >> Innate Immunity >> Chemokines >> Alpha Chemokines (CXC)

Relevance 

This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

 

Alternative names MCP1 antibody (ab18072)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

6347    (Human)

Omim

    

158105    (Human)

SwissProt

    

P13500    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: None
Constituents: PBS, pH 7.4

Form 

Lyophilised

Concentration 

0.200 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MCP1 antibody is on this datasheet. But please do contact us if you would like any reassurance!



References for MCP1 antibody (ab18072)

Specific publication references   This product has been used in:

Campbell SJ et al. Central nervous system injury triggers hepatic CC and CXC chemokine expression that is associated with leukocyte mobilization and recruitment to both the central nervous system and the liver. Am J Pathol 166:1487-97 (2005). PubMed: 15855648

If you publish research using ab18072 please let us know so that we can cite the reference on this datasheet.

 

Search PubMed (MEDLINE) for references to MCP1

 

MCP1 antibody - more information

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MCP1 antibody - related products:

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