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Product name
Anti-MCSF Receptor antibody
See all MCSF Receptor products (16) ...
Description
Rabbit polyclonal to MCSF Receptor
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Horse, Cow, Cat
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 955~972 (EQGDIAQPLLQPNNYQFC) of human MCSF Receptor.
EQGDIAQPLLQPNNYQFC
Positive control
Human placenta (WB).
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Immunology >> Innate Immunity >> Cytokines >> CSFs
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Cardiovascular >> Angiogenesis >> Cytokines >> Other
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Western blot - MCSF Receptor antibody (ab37858)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab37858 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000.ELISA: 1/1000.
WB: 1/100 - 1/500. Detects a band of approximately 108 kDa (predicted molecular weight: 108 kDa).
Target
Function
Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
Tissue specificity
Expressed in bone marrow and in differentiated blood mononuclear cells.
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
Cellular localization
Membrane.
Target information above from: UniProt accessionP07333
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- C FMS antibody
- C FMS antibody
- CD 115 antibody
see all
Database links
- Entrez Gene: 509418 Cow
- Entrez Gene: 1436 Human
- Entrez Gene: 12978 Mouse
- Entrez Gene: 307403 Rat
- Omim: 164770 Human
- SwissProt: P13369 Cat
- SwissProt: Q1JP72 Cow
- SwissProt: Q4W447 Horse
see all
Anti-MCSF Receptor antibody images:
Western blot - MCSF Receptor antibody (ab37858)
Anti-MCSF Receptor antibody (ab37858) + Human placenta
Secondary
HRP-anti-rabbit.
developed using the ECL technique
Predicted band size : 108 kDa
Observed band size : 108 kDa
References for Anti-MCSF Receptor antibody (ab37858)
This product has been referenced in:
- James DE et al. The relative timing of exposure to phagocytosable particulates and to osteoclastogenic cytokines is critically important in the determination of myeloid cell fate. J Immunol 185:1265-73 (2010). WB; Human.Read more (PubMed: 20543106) »
See 1 publication for this product
Publishing research using ab37858? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"