Overview
- Product nameAnti-MCSF antibody [MM0466-3V17]See all MCSF primary antibodies ...
- DescriptionMouse monoclonal [MM0466-3V17] to MCSF
- Tested applicationsWB, Neutralising more details
- Species reactivityReacts with: Human
- Immunogen
Recombinant full length Human MCSF
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: PBS -
Concentration information loading... - PurityProtein G purified
- Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
- Clonality Monoclonal
- Clone numberMM0466-3V17
- IsotypeIgG2
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab89571 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/500 - 1/1000. Predicted molecular weight: 60 kDa. |
| Neutralising | Neut: Use at an assay dependent dilution. |
Target
- FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
- Post-translational
modificationsGlycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.
Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated. - Cellular localizationCell membrane and Secreted > extracellular space.
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Database links
- Entrez Gene: 1435 Human
- Omim: 120420 Human
- SwissProt: P09603 Human
- Unigene: 591402 Human
Target information above from: UniProt accession
P09603
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Colony stimulating factor 1 (macrophage) antibodyColony stimulating factor 1 antibodyColony stimulating factor macrophage specific antibody
- CSF 1 antibodyCSF-1 antibodyCSF1 antibodyCSF1_HUMAN antibodyCsfm antibodyLanimostim antibodyM CSF antibodyM-CSF antibodyMacrophage Colony Stimulating Factor 1 antibodyMacrophage colony stimulating factor antibodyMCSF antibodyMGC31930 antibodyProcessed macrophage colony-stimulating factor 1 antibody
see all
References for Anti-MCSF antibody [MM0466-3V17] (ab89571)
ab89571 has not yet been referenced specifically in any publications.
