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Overview

  • Product nameAnti-MCSF antibodySee all MCSF primary antibodies ...
  • Description
    Rabbit polyclonal to MCSF
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the C-terminal region of Human MCSF conjugated to KLH (NP_000748.3).

  • Positive controlNCI-H460 cell line lysates, 293 cell lysates (transiently transfected with the MCSF gene).

Properties

Applications

Our Abpromise guarantee covers the use of ab93335 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 60 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
    • Post-translational
      modifications      Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.
      Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.
    • Cellular localizationCell membrane and Secreted > extracellular space.

      • Target information above from: UniProt accession P09603 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          Colony stimulating factor 1 (macrophage) antibodyColony stimulating factor 1 antibodyColony stimulating factor macrophage specific antibody
          CSF 1 antibodyCSF-1 antibodyCSF1 antibodyCSF1_HUMAN antibodyCsfm antibodyLanimostim antibodyM CSF antibodyM-CSF antibodyMacrophage Colony Stimulating Factor 1 antibodyMacrophage colony stimulating factor antibodyMCSF antibodyMGC31930 antibodyProcessed macrophage colony-stimulating factor 1 antibody
        see all

      Anti-MCSF antibody images

      • Western blot - MCSF antibody (ab93335)
        Western blot - MCSF antibody (ab93335)
        Anti-MCSF antibody (ab93335) at 1/100 dilution + NCI-H460 cell line lysates at 35 µg

        Predicted band size : 60 kDa
      • Western blot - MCSF antibody (ab93335)
        Western blot - MCSF antibody (ab93335)
        All lanes : Anti-MCSF antibody (ab93335) at 1/100 dilution

        Lane 1 : 293 cell lysates, nontransfected
        Lane 2 : 293 cell lysates, transiently transfected with the MCSF gene

        Lysates/proteins at 2 µg per lane.


        Predicted band size : 60 kDa

      References for Anti-MCSF antibody (ab93335)

      ab93335 has not yet been referenced specifically in any publications.

      Publishing research using ab93335 ? Please let us know so that we can cite the reference in this datasheet

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