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Anti-MCT2 antibody (ab81262)

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Overview

Product name

Anti-MCT2 antibody
See all MCT2 products (3) ...

Description

Rabbit polyclonal to MCT2

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide derived from human MCT2 protein

Positive control

Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.08% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of carbohydrates
Signal Transduction >> Metabolism >> Plasma Membrane >> Channels

Applications

Show applications key

Our Abpromise guarantee covers the use of ab81262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. MCT2 is a high affinity transporter that catalyzes the rapid transport of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate across the plasma membrane.

Cellular localization

Plasma membrane

Alternative names

  • MCT antibody
  • MonocarboxylateTransporter 2 antibody
  • MOT2 antibody
  • SLC16A7 antibody
  • Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody
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Database links

References for Anti-MCT2 antibody (ab81262)

ab81262 has not yet been referenced specifically in any publications.

Publishing research using ab81262? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"