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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MEF2A antibody (ab31172)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MEF2A antibody (ab31172)
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Product Name 

MEF2A antibody

 

See all MEF2A antibodies (15)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to MEF2A

Immunogen 

Synthetic peptide corresponding to amino acids 487-507 of Human MEF2.

Reacts with 

Hu

Predicted to react 
(species key)

Ms, Rat
(Due to sequence homology)

Specificity 

ab31172 recognizes myocyte enhancer factors-2 (MEF-2).

Tested applications 
(see key)

IHC-P, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/100 for 30 minutes at RT. Requires boiling of tissue sections in 10mM citrate buffer pH 6.0 for 10 minutes, followed by cooling at RT for 20 minutes.
WB: Use at an assay dependent dilution. Predicted molecular weight: 55 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

BC3H1 cells, Brain tissue.

Cellular localization 

Nuclear

Research areas 

Cardiovascular >> Heart >> Hypertrophy >> Transcription factors
Cardiovascular >> Heart >> Cardiogenesis >> Transcription factors/regulators
Chromatin and Nuclear Signaling >> Transcription >> Transcription Factors
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> Other
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Chromatin and Nuclear Signaling >> Transcription >> Polymerase associated factors >> Pol II Transcription >> Other
Neuroscience >> Neurology process >> Neurogenesis

Relevance 

MEF2A (myocyte specific enhancer factor 2) belongs to a family of DNA binding regulatory proteins. The MEF2 family of transcription factors is highly expressed in the brain when neurons undergo dendritic maturation and synapse formation. MEF2A is especially abundant in granule neurons of the cerebellar cortex throughout the period of synaptogenesis. MEF2A also has key roles in cardiac and skeletal muscle development.

 

Alternative names MEF2A antibody (ab31172)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

4205    (Human)
17258    (Mouse)
309957    (Rat)

GenBank

    

BC013437.2    (Human)

Omim

    

600660    (Human)

SwissProt

    

Q02078    (Human)
Q60929    (Mouse)
Q2MJT0    (Rat)

Unigene

    

268675    (Human)
162435    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 10mM PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.200 mg/ml

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MEF2A antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for MEF2A antibody images, references, products related to ab31172 and other tools.

 

MEF2A antibody images:

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MEF2A antibody (ab31172)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - MEF2A antibody (ab31172)

ab31172 at a 1:100 dilution staining MEF2A in human brain by Immunohistochemistry, Formalin Fixed Paraffin Embedded Tissue.

 
 

Search PubMed (MEDLINE) for references to MEF2A

 

MEF2A antibody - more information

Customer reviews (feedback) regarding MEF2A antibody

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MEF2A antibody - related products:

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