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Western blot - MEIS1 antibody (ab80593)
(enlarge)
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Product Name
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MEIS1 antibody
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See all MEIS1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to MEIS1
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Immunogen
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Synthetic peptide: C-SEDITRSANLTDQ, corresponding to internal sequence amino acids 198 - 210 of Human MEIS1 (NP_002389.1)
BLAST 'C-SEDITRSANLTDQ' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cow
(Due to sequence homology)
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Peptide ELISA: antibody detection limit dilution 1/32000
WB: Use at a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 43 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human Cerebral Cortex lysate
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Cellular localization
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Nuclear
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Research areas
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Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Myeloid Progenitor
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> HOX
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Relevance
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MEIS1 is a member of the TALE (three amino acid loop extension) family of homeodomain containing proteins. In addition to binding with other Hox proteins, MEIS1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA binding specificities. MEIS1 is implicated in oncogenesis as it is overexpressed as a result of adjacent retroviral insertion in BHX2 myeloid leukemias. It plays an important role in megakaryocytic gene expression.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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ab80593 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this MEIS1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for MEIS1 antibody images, references, products related to ab80593 and other tools.
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MEIS1 antibody images:
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 Western blot - MEIS1 antibody (ab80593)
MEIS1 antibody (ab80593) at 0.1 µg/ml + Human Cerebral Cortex lysate (in RIPA buffer) at 35 µg
Predicted band size : 43 kDa
Observed band size : 43 kDa
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Search PubMed (MEDLINE) for references to MEIS1
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MEIS1 antibody - more information
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Customer reviews (feedback) regarding MEIS1 antibody |
Customer FAQs regarding MEIS1 antibody |
Protocols for MEIS1 antibody |
Price and availability of products related to MEIS1 antibody |
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MEIS1 antibody - related products:
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MEIS1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about MEIS1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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