Anti-MEK1 + MEK2 antibody (ab89423)

Overview

• Product nameAnti-MEK1 + MEK2 antibodySee all MEK1 + MEK2 primary antibodies ...
• Description
  Rabbit polyclonal to MEK1 + MEK2
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide, corresponding to amino acids 210-220 of Human MEK1.

• Positive control293 cell lysate

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: 50% Glycerol, Tris buffered saline
• Concentration information loading...
• PurityProtein G purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • MAPK Pathway

Applications

Target

• RelevanceMitogen activated protein kinase kinase 1 + 2 (MAPKK1 + MAPKK2) are members of a protein kinase family that activate the ERK 1 + 2/MAPK enzymes by phosphorylating both residues within the threonine – glutamic acid – tyrosine (TEY) motif in the activation loop. MEK 1 + 2 are also activated by dual-phosphorylation, which occurs on serines 218 and 222, in the activation loop of the MEKs.
• Cellular localizationCytoplasmic
• Database links
  • Entrez Gene: 5605 Human
  • Entrez Gene: 5604 Human
  • Omim: 601263 Human
  • Omim: 176872 Human
  • SwissProt: P36507 Human
  • SwissProt: Q02750 Human

• Alternative names
  AA589381 antibodyDual specificity mitogen-activated protein kinase kinase 1 antibodyDual specificity mitogen-activated protein kinase kinase 2 antibody

  EC 2.7.12.2 antibodyERK activator kinase 1 antibodyERK activator kinase 2 antibodyFLJ26075 antibodyMAP kinase kinase 1 antibodyMAP kinase kinase 2 antibodyMAP2K1 antibodyMAP2K2 antibodyMAPK/ERK kinase 1 antibodyMAPK/ERK kinase 2 antibodyMAPKK1 antibodyMAPKK2 antibodyMEKK1 antibodyMitogen activated protein kinase kinase 1 antibodyMitogen activated protein kinase kinase 2 antibodyMitogen-activated protein kinase kinase 2, p45 antibodyMK2 antibodyMKK 1 antibodyMKK 2 antibodyMKK1 antibodyMKK2 antibodyPRKMK 1 antibodyPRKMK 2 antibodyPrkmk1 antibodyPrkmk2 antibodyprotein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) antibodyProtein kinase, mitogen-activated, kinase 1 antibodyProtein kinase, mitogen-activated, kinase 2 antibody

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Anti-MEK1 + MEK2 antibody images

• 

  Western blot - MEK1 + MEK2 antibody (ab89423)
  All lanes : Anti-MEK1 + MEK2 antibody (ab89423) at 1/1000 dilution
  
  Lane 1 : 293 cell lysate at 10 µg
  Lane 2 : 293 cell lysate at 20 µg
  Lane 3 : 293 cell lysate at 40 µg
  
  
  Predicted band size : 43-44 kDa
  
• 

  Immunoprecipitation - MEK1 + MEK2 antibody (ab89423)
  Immunoprecipitation with ab89423 (1:1000 dilution) using 30ng of His-MEK1 (Lane 1) and GST-MEK2 (Lane 2) recombinant proteins.