Anti-MEK1 + MEK2 (phospho S218 + S222) antibody (ab54494)
- Product nameAnti-MEK1 + MEK2 (phospho S218 + S222) antibodySee all MEK1 + MEK2 primary antibodies ...
- DescriptionRabbit polyclonal to MEK1 + MEK2 (phospho S218 + S222)
- Specificityab54494 recognizes the ~45 kDa MEK1 and MEK2 proteins phosphorylated at Ser218 and Ser222.
- Tested applicationsELISA, Dot Blot, WB more details
- Species reactivityReacts with: Human
A synthetic phosphopeptide corresponding to amino acids surrounding the Ser218 and Ser222 phosphorylation sites of human MEK1 + MEK2.
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES, pH 7.5
- Concentration information loading...
- PurityImmunogen affinity purified
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab54494 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/1000. Predicted molecular weight: 43/44 kDa. May also detect a higher molecular weight band.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- RelevanceMitogen activated protein kinase kinase 1 + 2 (MAPKK1 + MAPKK2) are members of a protein kinase family that activate the ERK 1 + 2/MAPK enzymes by phosphorylating both residues within the threonine – glutamic acid – tyrosine (TEY) motif in the activation loop. MEK 1 + 2 are also activated by dual-phosphorylation, which occurs on serines 218 and 222, in the activation loop of the MEKs.
- Cellular localizationCytoplasmic
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References for Anti-MEK1 + MEK2 (phospho S218 + S222) antibody (ab54494)
ab54494 has not yet been referenced specifically in any publications.