Anti-MEK7 antibody (ab5436)

Overview

• Product nameAnti-MEK7 antibodySee all MEK7 primary antibodies ...
• Description
  Rabbit polyclonal to MEK7
• Tested applicationsIHC-P, ELISA, WB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide conjugated to KLH, corresponding to amino acids 402-419 of Human MKK 7.

• Positive controlHL60 cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• PurityProtein G purified
• Purification notesThis antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Oxidative stress

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Kinases
  • Other

  • Signal Transduction
  • Protein Phosphorylation
  • Ser / Thr Kinases
  • MAPK Pathway

  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Immunology
  • Innate Immunity
  • TLR Signaling

  • Cell Biology
  • Other Antibodies
  • Oxidative Stress

Applications

Target

• FunctionStress activated, dual specificity kinase that activates the JUN kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3.
• Tissue specificityUbiquitous; with highest level of expression in skeletal muscle. Isoform 3 is found at low levels in placenta, fetal liver, and skeletal muscle.
• Sequence similaritiesBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
  Contains 1 protein kinase domain.
• Post-translational
  modificationsActivated by phosphorylation on Ser/Thr.
• Cellular localizationNucleus. Cytoplasm.

Target information above from: UniProt accession O14733 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 5609 Human
  • Omim: 603014 Human
  • SwissProt: O14733 Human
  • Unigene: 531754 Human

• Alternative names
  c Jun N terminal kinase kinase 2 antibodyc-Jun N-terminal kinase kinase 2 antibodyDual specificity mitogen activated protein kinase kinase 7 antibody

  Dual specificity mitogen-activated protein kinase kinase 7 antibodyJNK activating kinase 2 antibodyJNK kinase 2 antibodyJNK-activating kinase 2 antibodyJNKK 2 antibodyJnkk-2 antibodyJnkk2 antibodyMAP kinase kinase 7 antibodyMAP2K 7 antibodyMAP2K7 antibodyMAPK/ERK kinase 7 antibodyMAPKK 7 antibodyMAPKK-7 antibodyMAPKK7 antibodyMEK 7 antibodyMitogen activated protein kinase kinase 7 antibodyMKK 7 antibodyMKK-7 antibodyMKK7 antibodyMP2K7_HUMAN antibodyPRKMK 7 antibodyPRKMK-7 antibodyPRKMK7 antibodyProtein kinase mitogen activated kinase 7 antibodySek 2 antibodySek-2 antibodySek2 antibodySKK4 antibody

  see all

Anti-MEK7 antibody images

• 

  Western blot - MEK7 antibody (ab5436)
  
  
  Predicted band size : 55 kDa
  
  
  ab5436 at a 1/100 dilution staining approximately 47kDa band of MKK 7 in HL60 cell lysate by western blot (ECL).