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Storage instructions Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
Storage buffer Preservative: 0.09% Sodium azide Constituent: 99% PBS
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab116348 is purified through a Protein A column, followed by peptide affinity purification.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/100 - 1/500. Predicted molecular weight: 70 kDa.
Function Component of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7 (By similarity). Plays a role in caveolae kiss-and-run dynamics.
Sequence similarities Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. Contains 1 OPR domain. Contains 1 protein kinase domain.
Post-translational modifications Autophosphorylated.
Cellular localization Cytoplasm. Nucleus. Upon EGF stimulation, translocates into the nucleus.
Information by UniProt
MAPK/ERK kinase kinase 2 antibody
Anti-MEKK2 antibody images
Western blot - Anti-MEKK2 antibody (ab116348)
All lanes : Anti-MEKK2 antibody (ab116348) at 1/100 dilution Lane 1 : 293 cell lysates, non-transfected Lane 2 : 293 cell lysates, MEKK2 transfected Lysates/proteins at 2 µg per lane. Predicted band size : 70 kDa
References for Anti-MEKK2 antibody (ab116348)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"