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Products:Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Overview
Product name
MELK peptide (639-651)
See all MELK products (2) ...
Protein description
Synthetic peptide: KRLVEDILSSCKV, corresponding to amino acids 639-651 of Human MELK.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Concentration
Concentration information loading...
Sequence
KRLVEDILSS CKV
Research areas
Developmental Biology >> Embryogenesis >> Embryonic stem cells >> Surface molecules
Cell Biology >> Cell Cycle >> Cell Division >> Other cell division antibodies
Stem Cells >> Embryonic Stem Cells >> Intracellular
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Applications
Application notes
This peptide can be used with studies using ab9696.
Protein info
Function
Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.
Tissue specificity
Expressed in placenta, kidney, thymus, testis, ovary and intestine.
Sequence similarities
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 KA1 (kinase-associated) domain.
Contains 1 protein kinase domain.
Post-translational
modifications
Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.
Cellular localization
Cytoplasm.
Target information above from: UniProt accessionQ14680
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for MELK peptide (639-651) (ab23158)
ab23158 has not yet been referenced specifically in any publications.
Publishing research using ab23158? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"