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MELK peptide (639-651) (ab23158)

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Overview

Product name

MELK peptide (639-651)
See all MELK products (2) ...

Protein description

Synthetic peptide: KRLVEDILSSCKV, corresponding to amino acids 639-651 of Human MELK.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Concentration

Concentration information loading...

Sequence

KRLVEDILSS CKV

Applications

Application notes

This peptide can be used with studies using ab9696.

Protein info

Function

Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

Tissue specificity

Expressed in placenta, kidney, thymus, testis, ovary and intestine.

Sequence similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 KA1 (kinase-associated) domain.
Contains 1 protein kinase domain.

Post-translational
modifications

Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionQ14680 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for MELK peptide (639-651) (ab23158)

ab23158 has not yet been referenced specifically in any publications.

Publishing research using ab23158? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"