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Anti-MHC Class I H2 Kd antibody [1.B.548] (ab62226)

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Overview

Product name

Anti-MHC Class I H2 Kd antibody [1.B.548]
See all MHC Class I H2 Kd products (5) ...

Description

Mouse monoclonal [1.B.548] to MHC Class I H2 Kd

Specificity

ab62226 detects classical mouse MHC class I antigen, H2 Kd allele.

Tested applications

WB, Flow Cytmore details

Cross reactivity

Reacts with

Mouse

Immunogen

Full length MHC Class I H2 Kd protein (Mouse)

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 1.0% BSA, PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Primary antibody notes

MHC Class I H2 Kd is present on 100% of T-cells and B-cells including beta cells of Langerhans, etc. It is also present on endothelial and epithelial tissue.

Clonality

Monoclonal

Clone number

1.B.548

Isotype

IgG2b

Light chain type

kappa

Research areas

Immunology >> Adaptive Immunity >> MHC >> Class I

Applications

Show applications key

Our Abpromise guarantee covers the use of ab62226 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

MHC Class I H2 Kd is involved in the presentation of foreign antigens to the immune system. The “classical” MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant Beta2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.

Cellular localization

Cell Membrane

Alternative names

  • class I major histocompatibility antigen H 2Kd antibody
  • H 2 class I histocompatibility antigen K D alpha chain [Precursor] antibody
  • H 2K antibody
  • H2 K1 antibody
  • MHC class I H2 K b alpha 2 cell surface glycoprotein antibody
  • MHC class I heavy chain H2 K antibody
  • MHC H2 K transplantation antigen antibody
  • MHC K bm6 transplantation antigen antibody
see all

Database links

References for Anti-MHC Class I H2 Kd antibody [1.B.548] (ab62226)

ab62226 has not yet been referenced specifically in any publications.

Publishing research using ab62226? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"