Overview

  • Product nameAnti-MIIP antibodySee all MIIP primary antibodies ...
  • Description
    Rabbit polyclonal to MIIP
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 280-320 of Human MIIP

  • Positive control
    • ZR-75-1 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab103380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 43 kDa.

Target

  • RelevanceMIIP has 3 SEG (segments of low compositional complexity) domains, an RGD motif, and several potential phosphorylation sites. The C-terminal region of IGFBP2 interacts with a central 44-amino acid sequence of MIIP. MIIP inhibits glioma cells invasion and down-regulates adhesion- and motility-associated genes such as NFKB2 and ICAM1. It exhibits opposing effects to IGFBP2 on cell invasion. There are 2 named isoforms due to alternative splicing. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression. On the contrary, at protein level, isoform 2 is not detected in gliomas, suggesting that this isoform is unstable in glioma cells. Isoform 2 is degraded by the ubiquitin-proteasome pathway.
  • Database links
  • Alternative names
    • FLJ12438 antibody
    • FLJ38609 antibody
    • IGFBP 2 binding protein antibody
    • IGFBP2 binding protein antibody
    • IIP45 antibody
    • Invasion inhibitory protein 45 antibody
    • Migration and invasion inhibitory protein antibody
    • RP5 1077B9.4 antibody
    see all

Anti-MIIP antibody images

  • Anti-MIIP antibody (ab103380) at 1/100 dilution + ZR-75-1 cell lysate at 35 µg

    Predicted band size : 43 kDa

References for Anti-MIIP antibody (ab103380)

ab103380 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab103380.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"