Overview

  • Product name
  • Description
    Rabbit polyclonal to MKS1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-184 of Human MKS1 (AAH10061).

  • Positive control
    • Jurkat whole cell lysate; A431 and Raji cell lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab101506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 65 kDa.

Target

  • Function
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.
  • Involvement in disease
    Meckel syndrome 1
    Bardet-Biedl syndrome 13
  • Sequence similarities
    Contains 1 B9 domain.
  • Cellular localization
    Cytoplasm > cytoskeleton > cilium basal body. Cytoplasm > cytoskeleton > microtubule organizing center > centrosome. Localizes at the transition zone, a region between the basal body and the ciliary axoneme.
  • Information by UniProt
  • Database links
  • Alternative names
    • B8d3 antibody
    • BBS13 antibody
    • Dysencephalia splanchnocystica antibody
    • FABB proteome like protein antibody
    • FLJ20345 antibody
    • Gruber syndrome antibody
    • Meckel gruber syndrome antibody
    • Meckel gruber syndrome type 1 antibody
    • Meckel syndrome antibody
    • Meckel syndrome type 1 antibody
    • Meckel syndrome type 1 protein antibody
    • Meckel syndrome type 1 protein homolog antibody
    • MES antibody
    • MKS 1 antibody
    • MKS antibody
    • Mks1 antibody
    • MKS1_HUMAN antibody
    • POC12 antibody
    • POC12 centriolar protein homolog antibody
    see all

Images

  • Anti-MKS1 antibody (ab101506) at 1/2000 dilution + Jurkat whole cell lysate at 30 µg

    Predicted band size : 65 kDa

References

ab101506 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab101506.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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