ML130, NOD1 inhibitor (ab142177)
Key features and details
- Potent, selective, cell-permeable NOD1 inhibitor
- CAS Number: 799264-47-4
- Purity: > 97%
- Soluble in DMSO to 100 mM and in ethanol to 10 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ML130, NOD1 inhibitor -
Description
Potent, selective, cell-permeable NOD1 inhibitor -
Purity
> 97% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1974 ML130. 1974-25 is the same size as the 25 mg size of ab142177.
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CAS Number
799264-47-4 -
Chemical structure
Properties
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Chemical name
1-(4-Methylphenyl)sulfonylbenzimidazol-2-amine -
Molecular weight
287.34 -
Molecular formula
C14H13N3O2S -
PubChem identifier
1088438 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 10 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab142177 has been referenced in 2 publications.
- Wu J et al. Peptidoglycan-Mediated Bone Marrow Autonomic Neuropathy Impairs Hematopoietic Stem/Progenitor Cells via a NOD1-Dependent Pathway in db/db Mice. Stem Cells Int 2022:4249843 (2022). PubMed: 35966130
- Liu FY et al. The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats. Med Sci Monit 26:e924748 (2020). PubMed: 32855380