MMP13 peptide (Hinge Region) (ab44853)
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Our Abpromise guarantee covers the use of ab44853 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- CLG 3CLG3CLG3
- Collagenase 3Collagenase 3Collagenase3MANDP1Matrix metallopeptidase 13 (collagenase 3)Matrix Metalloproteinase 13Matrix Metalloproteinase 13Matrix metalloproteinase-13MMP 13MMP-13Mmp13MMP13_HUMAN
Defects in MMP13 are the cause of metaphyseal anadysplasia type 1 (MANDP1) [MIM:602111]. Metaphyseal anadysplasia consists of an abnormal bone development characterized by severe skeletal changes that, in contrast with the progressive course of most other skeletal dysplasias, resolve spontaneously with age. Clinical characteristics are evident from the first months of life and include slight shortness of stature and a mild varus deformity of the legs. Patients attain a normal stature in adolescence and show improvement or complete resolution of varus deformity of the legs and rhizomelic micromelia.
Contains 4 hemopexin-like domains.
References for MMP13 peptide (Hinge Region) (ab44853)
ab44853 has not yet been referenced specifically in any publications.