Anti-MMP3 antibody [SL-1 IID4] - BSA and Azide free (ab80949)

Overview

  • Product nameAnti-MMP3 antibody [SL-1 IID4] - BSA and Azide freeSee all MMP3 primary antibodies ...
  • Description
    Mouse monoclonal [SL-1 IID4] to MMP3 - BSA and Azide free
  • SpecificityReacts with both pro and active forms of MMP3
  • Tested applicationsWB, ICC/IF more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    APMA (4-Aminophenylmercuric acetate) activated Human MMP3

  • Positive control
    • Conditioned, serum-free medium from TPA treated human Endometrial cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab80949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 54 kDa.
AP Use at an assay dependent dilution.
ICC/IF Use at an assay dependent dilution.

Target

  • FunctionCan degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
  • Sequence similaritiesBelongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Target information above from: UniProt accession P08254 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
  • Alternative names
    • CHDS6 antibody
    • Matrix metalloproteinase 3 antibody
    • Matrix metalloproteinase-3 antibody
    • MGC126102 antibody
    • MGC126103 antibody
    • MGC126104 antibody
    • MMP-3 antibody
    • MMP3 antibody
    • MMP3_HUMAN antibody
    • Proteoglycanase antibody
    • SL-1 antibody
    • SL1 antibody
    • STMY antibody
    • STMY1 antibody
    • STR1 antibody
    • Stromelysin 1 antibody
    • Stromelysin-1 antibody
    • Transin 1 antibody
    • Transin-1 antibody
    see all

References for Anti-MMP3 antibody [SL-1 IID4] - BSA and Azide free (ab80949)

ab80949 has not yet been referenced specifically in any publications.

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