Anti-MMP7 antibody - Aminoterminal end (ab39001)


  • Product nameAnti-MMP7 antibody - Aminoterminal end
    See all MMP7 primary antibodies
  • Description
    Rabbit polyclonal to MMP7 - Aminoterminal end
  • Specificityab39001 recognizes the aminoterminal end of the active enzyme MMP7. It does not cross react with the other MMP family members.
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human, Pig
  • Immunogen

    Synthetic peptide corresponding to the aminoterminal end of human MMP7 active enzyme.

    (Peptide available as ab41049.)

  • Positive control
    • human MMP7, cell media from pig kidney, epithelial morphology (IL1 alpha treated).


Associated products


Our Abpromise guarantee covers the use of ab39001 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: 1/1000 when using colormetric substrates such as BCIP/NBT - 1/5000 when using chemiluminescent substrates. Predicted molecular weight: 29 kDa. When used against the reduced protein, ab39001 identifies bands at about 28 Kd, and 18Kd (the pro-form and active forms). Note: MMP7 does not appear to be produced by most normal quiescent cells, but treatment of many cell types with the phorbol ester TPA stimulates its production. Because of the low protein levels produced (pg/mL) concentration of cell culture media is often required to visualize the bands by Western Blotting. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionDegrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
    • Sequence similaritiesBelongs to the peptidase M10A family.
    • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • Cellular localizationSecreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • Database links
    • Alternative names
      • Matrilysin antibody
      • Matrin antibody
      • Matrix Metalloproteinase 7 antibody
      • Matrix metalloproteinase-7 antibody
      • MMP 7 antibody
      • MMP-7 antibody
      • MMP7 antibody
      • MMP7_HUMAN antibody
      • MPSL1 antibody
      • PUMP 1 antibody
      • Pump 1 protease antibody
      • Pump-1 protease antibody
      • PUMP1 antibody
      • Uterine matrilysin antibody
      • Uterine metalloproteinase antibody
      see all

    Anti-MMP7 antibody - Aminoterminal end images

    • All lanes : Anti-MMP7 antibody - Aminoterminal end (ab39001) at 1/1000 dilution

      Lane 1 : human MMP7
      Lane 2 : cell media from pig kidney, epithelial morphology (IL1 alpha treated).

      Predicted band size : 29 kDa
      Observed band size : 22,24,29 kDa (why is the actual band size different from the predicted?)

    References for Anti-MMP7 antibody - Aminoterminal end (ab39001)

    ab39001 has not yet been referenced specifically in any publications.

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