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  • Product nameAnti-MMP7 antibody [ID2]
    See all MMP7 primary antibodies
  • Description
    Mouse monoclonal [ID2] to MMP7
  • Specificityab3205 recognizes pro (latent) and active forms of MMP 7.
  • Tested applicationsICC/IF, IP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human matrilysin (PUMP-1).

  • Positive control
    • Conditioned, serum-free medium from (TPA-treated) human SW620 cells. Placenta, bladder, breast and ovarian carcinomas.



Our Abpromise guarantee covers the use of ab3205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 19266094
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Detects a band of approximately 18, 29.6 kDa.
IHC-P Use a concentration of 4 - 8 µg/ml.


  • FunctionDegrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • Sequence similaritiesBelongs to the peptidase M10A family.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Matrilysin antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

Anti-MMP7 antibody [ID2] images

  • Immunofluorescence analysis of HT29 cell lines which are resistant (HT29) or non-resistant (RHT29) to oxaliplatin. Cells were either untreated (control) or treated with oxaliplatin (OXA), and MMP7 was stained using ab3205. An AlexaFluor®594-conjugated anti-mouse IgG was used as the secondary antibody.

References for Anti-MMP7 antibody [ID2] (ab3205)

This product has been referenced in:
  • Servais EL  et al. Mesothelin overexpression promotes mesothelioma cell invasion and MMP-9 secretion in an orthotopic mouse model and in epithelioid pleural mesothelioma patients. Clin Cancer Res 18:2478-89 (2012). IHC-P ; Human . Read more (PubMed: 22371455) »
  • Ho BY  et al. Effects of monascus-fermented rice extract on malignant cell-associated neovascularization and intravasation determined using the chicken embryo chorioallantoic membrane model. Integr Cancer Ther 9:204-12 (2010). Read more (PubMed: 20356949) »

See all 3 Publications for this product

Product Wall

Thank you for sending me the image of your blot, I understand your question. As I previously mentioned, the predicted MW of the protein (precursor, prior to any post-translational modifications) is 29.6kDa. I have tried to find further information rega...

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