Anti-MMP7 antibody [SPM294], prediluted (ab17854)

Overview

  • Product nameAnti-MMP7 antibody [SPM294], predilutedSee all MMP7 primary antibodies ...
  • Description
    Mouse monoclonal [SPM294] to MMP7, prediluted
  • Tested applicationsIHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human matrilysin (MMP7/PUMP1).

  • Positive control
    • Conditioned, serum-free medium from TPA treated human Endometrial cells. Placenta. Bladder, breast, ovarian carcinomas.
  • General notesMolecular weight: ~28kDa (pro form) and ~18kDa (active form).

Properties

Applications

Our Abpromise guarantee covers the use of ab17854 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent dilution.

Target

  • FunctionDegrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • Sequence similaritiesBelongs to the peptidase M10A family.
  • DomainThe conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Matrilysin antibody
    • Matrilysin uterine antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine Matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

Anti-MMP7 antibody [SPM294], prediluted images

  • ab17854 MMP7/Matrilysin/PUMP1 staining in formalin-fixed human placenta (30min incubation at RT).

References for Anti-MMP7 antibody [SPM294], prediluted (ab17854)

ab17854 has not yet been referenced specifically in any publications.

Product Wall

Dear Marti, Thank you for your patience. Regarding ab17854 (MMP7 Ab SPM294), the concentration of this prediluted antibody (lot# 192961) is 8ug/ml.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"